Evidence map›Paper›PMID 32591011›Full record

ArticleGenetics, selection, evolution : GSE2020

Whole-genome sequencing of European autochthonous and commercial pig breeds allows the detection of signatures of selection for adaptation of genetic resources to different breeding and production systems.

Samuele Bovo, Anisa Ribani, Maria Muñoz, Estefania Alves, Jose P Araujo, Riccardo Bozzi, Marjeta Čandek-Potokar, Rui Charneca, Federica Di Palma, Graham Etherington and 21 more

Abstract read
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Article in Genetics, selection, evolution : GSE, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Computational analysis of non-synonymous SNPs in the sheep MC4R gene.Journal, genetic engineering & biotechnology · 2026
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  6. Methylation-associated mutagenesis underlies variation in the mutation spectrum across eukaryotes.Proceedings of the National Academy of Sciences of the United States of America · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors.

Samuele BovoDepartment of Agricultural and Food Sciences, Division of Animal Sciences, University of Bologna, Viale Fanin 46, 40127, Bologna, Italy.
Anisa RibaniDepartment of Agricultural and Food Sciences, Division of Animal Sciences, University of Bologna, Viale Fanin 46, 40127, Bologna, Italy.
Maria MuñozDepartamento Mejora Genética Animal, INIA, Crta. de la Coruña km. 7,5, 28040, Madrid, Spain.
Estefania AlvesDepartamento Mejora Genética Animal, INIA, Crta. de la Coruña km. 7,5, 28040, Madrid, Spain.
Jose P AraujoCentro de Investigação de Montanha (CIMO), Instituto Politécnico de Viana do Castelo, Escola Superior Agrária, Refóios do Lima, 4990-706, Ponte de Lima, Portugal.
Riccardo BozziDAGRI - Animal Science Section, Università di Firenze, Via delle Cascine 5, 50144, Florence, Italy.
Marjeta Čandek-PotokarKmetijski Inštitut Slovenije, Hacquetova 17, 1000, Ljubljana, Slovenia.
Rui CharnecaInstituto de Ciências Agrárias e Ambientais Mediterrânicas (ICAAM), Universidade de Évora, Polo da Mitra, Apartado 94, 7006-554, Évora, Portugal.
Federica Di PalmaEarlham Institute, Norwich Research Park, Colney Lane, Norwich, NR47UZ, UK.
Graham EtheringtonEarlham Institute, Norwich Research Park, Colney Lane, Norwich, NR47UZ, UK.
Ana I FernandezDepartamento Mejora Genética Animal, INIA, Crta. de la Coruña km. 7,5, 28040, Madrid, Spain.
Fabián GarcíaDepartamento Mejora Genética Animal, INIA, Crta. de la Coruña km. 7,5, 28040, Madrid, Spain.
Juan García-CascoDepartamento Mejora Genética Animal, INIA, Crta. de la Coruña km. 7,5, 28040, Madrid, Spain.
Danijel KarolyiDepartment of Animal Science, Faculty of Agriculture, University of Zagreb, Svetošimunska c. 25, 10000, Zagreb, Croatia.
Maurizio GalloAssociazione Nazionale Allevatori Suini (ANAS), Via Nizza 53, 00198, Rome, Italy.
Vladimir MargetaFaculty of Agrobiotechnical Sciences, University of Osijek, Vladimira Preloga 1, 31000, Osijek, Croatia.
José Manuel MartinsInstituto de Ciências Agrárias e Ambientais Mediterrânicas (ICAAM), Universidade de Évora, Polo da Mitra, Apartado 94, 7006-554, Évora, Portugal.
Marie J MercatIFIP Institut du porc, La Motte au Vicomte, BP 35104, 35651, Le Rheu Cedex, France.
Giulia MoscatelliDepartment of Agricultural and Food Sciences, Division of Animal Sciences, University of Bologna, Viale Fanin 46, 40127, Bologna, Italy.
Yolanda NúñezDepartamento Mejora Genética Animal, INIA, Crta. de la Coruña km. 7,5, 28040, Madrid, Spain.
Raquel QuintanillaPrograma de Genética y Mejora Animal, IRTA, Torre Marimon, 08140, Caldes de Montbui, Barcelona, Spain.
Čedomir RadovićDepartment of Pig Breeding and Genetics, Institute for Animal Husbandry, Belgrade-Zemun, 11080, Serbia.
Violeta RazmaiteAnimal Science Institute, Lithuanian University of Health Sciences, Baisogala, Lithuania.
Juliette RiquetGenPhySE, INRAE, Université de Toulouse, Chemin de Borde-Rouge 24, Auzeville Tolosane, 31326, Castanet Tolosan, France.
Radomir SavićFaculty of Agriculture, University of Belgrade, Nemanjina 6, Belgrade-Zemun, 11080, Serbia.
Giuseppina SchiavoDepartment of Agricultural and Food Sciences, Division of Animal Sciences, University of Bologna, Viale Fanin 46, 40127, Bologna, Italy.
Graziano UsaiAGRIS SARDEGNA, Loc. Bonassai, 07100, Sassari, Italy.
Valerio J UtzeriDepartment of Agricultural and Food Sciences, Division of Animal Sciences, University of Bologna, Viale Fanin 46, 40127, Bologna, Italy.
Christoph ZimmerBäuerliche Erzeugergemeinschaft Schwäbisch Hall, Schwäbisch Hall, Germany.
Cristina OviloDepartamento Mejora Genética Animal, INIA, Crta. de la Coruña km. 7,5, 28040, Madrid, Spain.
Luca FontanesiDepartment of Agricultural and Food Sciences, Division of Animal Sciences, University of Bologna, Viale Fanin 46, 40127, Bologna, Italy. luca.fontanesi@unibo.it.ORCID http://orcid.org/0000-0001-7050-3760

Funding

Horizon 2020 634476
6 · The paper itself

Abstract

backgroundNatural and artificial directional selection in cosmopolitan and autochthonous pig breeds and wild boars have shaped their genomes and resulted in a reservoir of animal genetic diversity. Signatures of selection are the result of these selection events that have contributed to the adaptation of breeds to different environments and production systems. In this study, we analysed the genome variability of 19 European autochthonous pig breeds (Alentejana, Bísara, Majorcan Black, Basque, Gascon, Apulo-Calabrese, Casertana, Cinta Senese, Mora Romagnola, Nero Siciliano, Sarda, Krškopolje pig, Black Slavonian, Turopolje, Moravka, Swallow-Bellied Mangalitsa, Schwäbisch-Hällisches Schwein, Lithuanian indigenous wattle and Lithuanian White old type) from nine countries, three European commercial breeds (Italian Large White, Italian Landrace and Italian Duroc), and European wild boars, by mining whole-genome sequencing data obtained by using a DNA-pool sequencing approach. Signatures of selection were identified by using a single-breed approach with two statistics [within-breed pooled heterozygosity (H

resultsWe detected more than 22 million single nucleotide polymorphisms (SNPs) across the 23 compared populations and identified 359 chromosome regions showing signatures of selection. These regions harbour genes that are already known or new genes that are under selection and relevant for the domestication process in this species, and that affect several morphological and physiological traits (e.g. coat colours and patterns, body size, number of vertebrae and teats, ear size and conformation, reproductive traits, growth and fat deposition traits). Wild boar related signatures of selection were detected across all the genome of several autochthonous breeds, which suggests that crossbreeding (accidental or deliberate) occurred with wild boars.

conclusionsOur findings provide a catalogue of genetic variants of many European pig populations and identify genome regions that can explain, at least in part, the phenotypic diversity of these genetic resources.

Indexed as

AcclimatizationAdaptation, PhysiologicalAlgorithmsAnimalsBreedingDomesticationEuropeFemaleGenomeGenomicsGenotypeGenotyping TechniquesMaleModels, GeneticPhenotypePolymorphism, Single Nucleotide

Identifiers

PMID32591011
PMCPMC7318759

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