Evidence map›Paper›PMID 32591007›Full record

ArticleTrials2020

INdividual Vocational and Educational Support Trial (INVEST) for young people with borderline personality disorder: study protocol for a randomised controlled trial.

Andrew M Chanen, Katie Nicol, Jennifer K Betts, Gary R Bond, Cathrine Mihalopoulos, Henry J Jackson, Katherine N Thompson, Martina Jovev, Hok Pan Yuen, Gina Chinnery and 5 more

Open access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
0.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
  7. Early Intervention for Personality Disorder.Focus (American Psychiatric Publishing) · 2022
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 2 countries.

Andrew M ChanenOrygen, 35 Poplar Road, Parkville, Melbourne, VIC, 3052, Australia. andrew.chanen@orygen.org.au.ORCID http://orcid.org/0000-0003-4468-622X
Katie NicolOrygen, 35 Poplar Road, Parkville, Melbourne, VIC, 3052, Australia.
Jennifer K BettsOrygen, 35 Poplar Road, Parkville, Melbourne, VIC, 3052, Australia.
Gary R BondIPS Employment Center, Rockville Institute and Westat Inc., 85 Mechanic Street, Suite C3-1, Box 4A, Lebanon, NH, 03766, USA.
Cathrine MihalopoulosDeakin Health Economics, Centre for Population Health Research, Deakin University, Geelong, VIC, 3220, Australia.
Henry J JacksonMelbourne School of Psychological Sciences, Redmond Barry Building, The University of Melbourne, Parkville, Melbourne, VIC, 3010, Australia.
Katherine N ThompsonOrygen, 35 Poplar Road, Parkville, Melbourne, VIC, 3052, Australia.
Martina JovevOrygen, 35 Poplar Road, Parkville, Melbourne, VIC, 3052, Australia.
Hok Pan YuenOrygen, 35 Poplar Road, Parkville, Melbourne, VIC, 3052, Australia.
Gina ChinneryOrygen, 35 Poplar Road, Parkville, Melbourne, VIC, 3052, Australia.
Judith RingTravancore School, 35 Poplar Road, Parkville, Melbourne, VIC, 3052, Australia.
Kelly AllottOrygen, 35 Poplar Road, Parkville, Melbourne, VIC, 3052, Australia.
Louise McCutcheonOrygen, 35 Poplar Road, Parkville, Melbourne, VIC, 3052, Australia.
Ashleigh P SalmonOrygen, 35 Poplar Road, Parkville, Melbourne, VIC, 3052, Australia.
Eoin KillackeyOrygen, 35 Poplar Road, Parkville, Melbourne, VIC, 3052, Australia.
The University of Melbourne · AUDeakin University · AUOrygen · AUOrygen Youth Health · AUWestat (United States) · US

Funding

National Health and Medical Research Council APP1144022
6 · The paper itself

Abstract

backgroundThe clinical onset of borderline personality disorder (BPD) usually occurs in young people (aged 12-25 years) and commonly leads to difficulty achieving and maintaining vocational (education and/or employment) engagement. While current psychosocial interventions lead to improvements in psychopathology, they have little effect upon functioning. Individual Placement and Support (IPS) is a client-driven model that assists individuals with severe mental illness to engage with education and/or employment appropriate to their personal goals, and that provides ongoing support to maintain this engagement. The objective of the INdividual Vocational and Educational Support Trial (INVEST) is to evaluate the effectiveness of adding IPS to an evidence-based early intervention programme for BPD, with the aim of improving vocational outcomes. METHODS/

designINVEST is a single-blind, parallel-groups, randomised controlled trial (RCT). The randomisation is stratified by gender and age and uses random permuted blocks. The interventions are 39 weeks of either IPS, or 'usual vocational services' (UVS). Participants will comprise 108 help-seeking young people (aged 15-25 years) with three or more DSM-5 BPD features and a desire to study or work, recruited from the Helping Young People Early (HYPE) early intervention programme for BPD at Orygen, in Melbourne, Australia. All participants will receive the HYPE intervention. After baseline assessment, staff who are blind to the intervention group allocation will conduct assessments at 13, 26, 39 and 52 weeks. At the 52-week primary endpoint, the primary outcome is the number of days in mainstream education/employment since baseline. Secondary outcomes include the cost-effectiveness of the intervention, quality of life, and BPD severity. DISCUSSION: Current treatments for BPD have little impact on vocational outcomes and enduring functional impairment is prevalent among this patient group. IPS is a targeted functional intervention, which has proven effective in improving vocational outcomes for adults and young people with psychotic disorders. This trial will investigate whether IPS is effective for improving vocational (employment and educational) outcomes among young people with subthreshold or full-syndrome BPD.

trial registrationAustralian New Zealand Clinical Trials Registry, ID: ACTRN12619001220156 . 13 September 2019.

Indexed as

EducationEmploymentAdolescentAdultAustraliaBorderline Personality DisorderCommunity Mental Health ServicesCost-Benefit AnalysisEarly Medical InterventionHumansOutcome Assessment, Health CareQuality of LifeRandomized Controlled Trials as TopicRehabilitation, VocationalSingle-Blind MethodYoung AdultAdolescentsBorderline personality disorderEarly interventionEducationEmploymentIndividual placement and supportYoung adultsYouth

Identifiers

PMID32591007
PMCPMC7320570
OpenAlexW3037688001

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.