Evidence map›Paper›PMID 32590938›Full record

ArticleBMC genomics2020

Transcriptomic analysis reveals hub genes and subnetworks related to ROS metabolism in Hylocereus undatus through novel superoxide scavenger trypsin treatment during storage.

Xin Li, Xueru Liu, Xinyue Pang, Yong Yin, Huichun Yu, Yunxia Yuan, Bairu Li

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC genomics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Xin LiCollege of Food and Bioengineering, Henan University of Science and Technology, No. 263, Kaiyuan Avenue, Luolong District, Luoyang city, 471023, Henan, China. lixin@haust.edu.cn.ORCID http://orcid.org/0000-0002-5976-2988
Xueru LiuCollege of Food and Bioengineering, Henan University of Science and Technology, No. 263, Kaiyuan Avenue, Luolong District, Luoyang city, 471023, Henan, China.
Xinyue PangMinistry of Education Key Laboratory of Cell Activities and Stress Adaptations, Lanzhou University, Lanzhou, 730000, China.
Yong YinCollege of Food and Bioengineering, Henan University of Science and Technology, No. 263, Kaiyuan Avenue, Luolong District, Luoyang city, 471023, Henan, China.
Huichun YuCollege of Food and Bioengineering, Henan University of Science and Technology, No. 263, Kaiyuan Avenue, Luolong District, Luoyang city, 471023, Henan, China.
Yunxia YuanCollege of Food and Bioengineering, Henan University of Science and Technology, No. 263, Kaiyuan Avenue, Luolong District, Luoyang city, 471023, Henan, China.
Bairu LiCollege of Food and Bioengineering, Henan University of Science and Technology, No. 263, Kaiyuan Avenue, Luolong District, Luoyang city, 471023, Henan, China.
Henan University of Science and Technology · CN

Funding

National Key Research and Development Program of China 2017YFC1600802Natural Science Foundation of Henan Province 182300410083Natural Science Program of the Educational Commission of Henan Province of China 18A310013Science and Technique Foundation of Henan Province 182102310644State Key Laboratory of Cotton Biology Open Fund CB2018A22
6 · The paper itself

Abstract

backgroundIt was demonstrated in our previous research that trypsin scavenges superoxide anions. In this study, the mechanisms of storage quality improvement by trypsin were evaluated in H. undatus.

resultsTrypsin significantly delayed the weight loss and decreased the levels of ROS and membrane lipid peroxidation. Transcriptome profiles of H. undatus treated with trypsin revealed the pathways and regulatory mechanisms of ROS genes that were up- or downregulated following trypsin treatment by gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes pathway (KEGG) enrichment analyses. The current results showed that through the regulation of the expression of hub redox enzymes, especially thioredoxin-related proteins, trypsin can maintain low levels of endogenous active oxygen species, reduce malondialdehyde content and delay fruit aging. In addition, the results of protein-protein interaction networks suggested that the downregulated NAD(P) H and lignin pathways might be the key regulatory mechanisms governed by trypsin.

conclusionsTrypsin significantly prolonged the storage life of H. undatus through regulatory on the endogenous ROS metabolism. As a new biopreservative, trypsin is highly efficient, safe and economical. Therefore, trypsin possesses technical feasibility for the quality control of fruit storage.

Indexed as

CactaceaeFood QualityFood StorageGene Expression ProfilingGene Expression Regulation, NeoplasticGene Regulatory NetworksHigh-Throughput Nucleotide SequencingMalondialdehydeMolecular Sequence AnnotationPlant ProteinsProtein Interaction MapsReactive Oxygen SpeciesSequence Analysis, RNATrypsinMalondialdehydePlant ProteinsReactive Oxygen SpeciesTrypsinGOHylocereus undatus (H. undatus)KEGGProtein-protein interaction (PPI)Reactive oxygen species (ROS)StorageTrypsin

Identifiers

PMID32590938
PMCPMC7318492
OpenAlexW3037718476

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.