Evidence map›Paper›PMID 32590911›Full record

ArticleJournal of diabetes science and technology2021

Evaluation of Opportunities and Limitations of Mid-Infrared Skin Spectroscopy for Noninvasive Blood Glucose Monitoring.

Sven Delbeck, H Michael Heise

Abstract read
In one paragraph

Article in Journal of diabetes science and technology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sven DelbeckSouth-Westphalia University of Applied Sciences, Interdisciplinary Center for Life Sciences, Iserlohn, Germany.ORCID 0000-0003-3004-5835
H Michael HeiseSouth-Westphalia University of Applied Sciences, Interdisciplinary Center for Life Sciences, Iserlohn, Germany.ORCID 0000-0001-7397-9289

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA wide range of optical techniques has recently been presented for the development of noninvasive methods for blood glucose sensing based on multivariate skin spectrum analysis, and most recent studies are reviewed in short by us. The vibrational spectral fingerprints of glucose, as especially found in the mid-infrared or Raman spectrum, have been suggested for achieving largest selectivity for the development of noninvasive blood glucose methods.

methodsHere, the different aspects on integral skin measurements are presented, which are much dependent on the absorption characteristics of water as the main skin constituent. In particular, different mid-infrared measurement techniques as realized recently are discussed. The limitations of the use of the attenuated total reflection technique in particular are elaborated, and confounding skin or saliva spectral features are illustrated and discussed in the light of recently published works, claiming that the attenuated total reflection technique can be utilized for noninvasive measurements.

resultsIt will be shown that the penetration depth of the infrared radiation with wavelengths around 10 µm is the essential parameter, which can be modulated by different measurement techniques as with photothermal or diffuse reflection. However, the law of physics is limiting the option of using the attenuated total reflection technique with waveguides from diamond or similar optical materials.

conclusionsThere are confounding features from mucosa,

Indexed as

Blood GlucoseBlood Glucose Self-MonitoringGlucoseHumansSkinSpectrophotometry, InfraredBlood GlucoseGlucoseattenuated total reflectionin vivo spectroscopymid-infrared spectroscopynoninvasive blood glucose assayspenetration depth simulationskin and oral mucosa

Identifiers

PMID32590911
PMCPMC7780363

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