Evidence map›Paper›PMID 32590819›Full record

Observational studyMedicine2020

Critically ill patients with COVID-19 with ECMO and artificial liver plasma exchange: A retrospective study.

Jian Liu, Yong-Quan Dong, Jie Yin, Guojun He, Xiaoxin Wu, Jianping Li, Yunqing Qiu, Xuelin He

Open access · goldAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
0.5field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Blood purification could tackle COVID-19?Journal of intensive care · 2021
    Article
  6. COVID-19 and Indirect Liver Injury: A Narrative Synthesis of the Evidence.Journal of clinical and translational hepatology · 2021
    Review
  7. Article
  8. Combination therapy with plasma exchange and glucocorticoid may be effective for severe COVID-19 infection: A retrospective observational study.Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy · 2021
    Observational
  9. Review
  10. Article
  11. Review
  12. Veno-Venous Extracorporeal Membrane Oxygenation in COVID-19-Where Are We Now?International journal of environmental research and public health · 2021
    Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Jian LiuDepartment of Intensive Care Unit, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou.
Yong-Quan DongDepartment of Respiratory Disease, Yinzhou No.2 Hospital, Ningbo.
Jie YinDepartment of Radiation Oncology.
Guojun HeDepartment of Intensive Care Unit, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou.
Xiaoxin WuDepartment of Infectious Diseases.
Jianping LiDepartment of Traditional Chinese Medicine.ORCID 0000-0003-1666-4664
Yunqing QiuDepartment of Infectious Diseases.
Xuelin HeDepartment of Kidney Disease Center, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, China.
Zhejiang University · CNFirst Affiliated Hospital Zhejiang University · CNNingbo No. 2 Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

COVID-19 is an emerging infectious disease capable of causing severe pneumonia. We aimed to characterize a group of critically ill patients in a single-center study.This was a retrospective case series of 23 patients with confirmed COVID-19-related critical illness in the intensive care unit (ICU) of a hospital in Hangzhou Zhejiang Province between January 22 and March 20, 2020.Of the 23 critically ill patients, the median age was 66 years (interquartile range [IQR] 59-80 years). The median time from disease onset to ICU admission was 10 days (IQR 6-11 days), to mechanical ventilation (MV) was 11 days (IQR 7.75-13 days), to artificial liver plasma exchange was 12 days (IQR 9.75-14.75 days), and to extracorporeal membrane oxygenation (ECMO) was 22 days (IQR 17.5-30 days). Nine patients required high flow oxygen. Fourteen patients received MV. Six required ECMO. Nine received artificial liver plasma exchange. Mortality was 0 at day 28.Mortality was 0 at day 28 in our single-center study. Extracorporeal membrane oxygenation reduced the requirements for ventilator support. Artificial liver plasma exchange significantly reduced inflammatory cytokine levels. These supportive therapies helped to extend the patients' survival times and increase the chance of follow-up treatments.

Indexed as

Extracorporeal Membrane OxygenationLiver, ArtificialAgedAged, 80 and overCoronavirus InfectionsCOVID-19Critical IllnessFemaleHumansMaleMiddle AgedPandemicsPneumonia, ViralRetrospective Studies

Identifiers

PMID32590819
PMCPMC7328989
OpenAlexW3037395294

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.