Evidence map›Paper›PMID 32590656›Full record

ArticlePlastic and reconstructive surgery2020

Long-Term Effect of Multiple Operations on Psychosocial Function in Teenage Cleft Lip and Palate Patients.

Hi'ilani M K Potemra, Johnny Lin, Anthony A Bertrand, Fransia S De Leon, Jake A Alford, Allison C Hu, Libby Wilson, Justine C Lee

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Plastic and reconstructive surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Association of Patient-Reported Anxiety and Pain After Alveolar Bone Grafting.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2024
    Article
  5. Article
  6. Article
  7. COVID-19 Pandemic Associated With Increased Self-reported Depressive Symptoms in Patients With Congenital Craniofacial Diagnoses.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2023
    Article
  8. Article
  9. Article
  10. Wnt7a promotes muscle regeneration in branchiomeric orbicularis oris muscle.International journal of clinical and experimental pathology · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Hi'ilani M K PotemraFrom the Division of Plastic and Reconstructive Surgery, University of California, Los Angeles, David Geffen School of Medicine; the Institute for Digital Research and Education, Department of Statistics, University of California, Los Angeles; and the Cleft Palate Program, Orthopaedic Institute for Children.
Johnny LinFrom the Division of Plastic and Reconstructive Surgery, University of California, Los Angeles, David Geffen School of Medicine; the Institute for Digital Research and Education, Department of Statistics, University of California, Los Angeles; and the Cleft Palate Program, Orthopaedic Institute for Children.
Anthony A BertrandFrom the Division of Plastic and Reconstructive Surgery, University of California, Los Angeles, David Geffen School of Medicine; the Institute for Digital Research and Education, Department of Statistics, University of California, Los Angeles; and the Cleft Palate Program, Orthopaedic Institute for Children.
Fransia S De LeonFrom the Division of Plastic and Reconstructive Surgery, University of California, Los Angeles, David Geffen School of Medicine; the Institute for Digital Research and Education, Department of Statistics, University of California, Los Angeles; and the Cleft Palate Program, Orthopaedic Institute for Children.
Jake A AlfordFrom the Division of Plastic and Reconstructive Surgery, University of California, Los Angeles, David Geffen School of Medicine; the Institute for Digital Research and Education, Department of Statistics, University of California, Los Angeles; and the Cleft Palate Program, Orthopaedic Institute for Children.
Allison C HuFrom the Division of Plastic and Reconstructive Surgery, University of California, Los Angeles, David Geffen School of Medicine; the Institute for Digital Research and Education, Department of Statistics, University of California, Los Angeles; and the Cleft Palate Program, Orthopaedic Institute for Children.
Libby WilsonFrom the Division of Plastic and Reconstructive Surgery, University of California, Los Angeles, David Geffen School of Medicine; the Institute for Digital Research and Education, Department of Statistics, University of California, Los Angeles; and the Cleft Palate Program, Orthopaedic Institute for Children.
Justine C LeeFrom the Division of Plastic and Reconstructive Surgery, University of California, Los Angeles, David Geffen School of Medicine; the Institute for Digital Research and Education, Department of Statistics, University of California, Los Angeles; and the Cleft Palate Program, Orthopaedic Institute for Children.
Orthopaedic Institute for Children · USUniversity of California, Los Angeles · US

Funding

UCLA Clinical Translational Science InstituteUL1TR001881 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARLEEN F. BROWN, ARASH NAEIM · 2016 to 2026
$118.1M
PRECLINICAL EVALUATION OF NANOPARTICULATE MINERALIZED COLLAGEN GLYCOSAMINOGLYCAN MATERIALS IN CALVARIAL REGENERATIONR01DE028098 · NIDCR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LEE, JUSTINE CHIA · 2019 to 2023
$1.9M
BLRD VA IK2 BX002442NCATS NIH HHS UL1 TR001881NIDCR NIH HHS R01 DE028098
6 · The paper itself

Abstract

backgroundCleft lip and palate patients undergo a significant number of interventions during their childhood and adolescence. Although the intention of such interventions is to improve psychosocial functioning, there exists a paucity of data on the psychosocial outcomes of the burden of care on cleft children. In this work, the long-term effects of quantity and timing of childhood operations on teenagers with cleft lip and palate were evaluated.

methodsCleft lip and palate patients (aged 14 to 17 years; n = 55) and an age-matched unaffected cohort (n = 14) prospectively enrolled from two institutions were administered the anger, anxiety, and depressive symptoms instruments from the Pediatric Patient-Reported Outcomes Measurement Information System. Total number of operations and operations stratified by age groups (0 to 7, 8 to 10, 11 to 13, and 14 to 17 years) were evaluated in relationship to instrument scores. Descriptive statistics, independent t tests, Pearson correlations, and multiple linear regression analyses were conducted.

resultsNo differences in overall psychosocial functioning were found between the cleft lip and palate and comparison groups. Total quantity of childhood operations did not correlate to psychosocial functioning of cleft lip and palate teenagers. However, multiple linear regression analyses demonstrated that increased number of operations in the 8- to 10-year-old age range predicted increased anxiety and depressive symptoms in teenagers (β = 0.38, p = 0.009; and β = 0.29, p = 0.03, respectively).

conclusionsIt was previously reported by the authors' group that the 8- to 10-year-old age range is an at-risk period for psychosocial distress in children with craniofacial anomalies. Their current work demonstrates that increased number of operations during this time frame may result in long-term consequences in anxiety and depression in cleft lip and palate patients. CLINICAL QUESTION/LEVEL OF EVIDENCE: Risk, II.

Indexed as

AdolescentAnxietyChildChild, PreschoolCleft LipCleft PalateDepressionFemaleHumansInfantMaleRegression AnalysisSurgical Procedures, Operative

Identifiers

PMID32590656
PMCPMC10659106
OpenAlexW3037550426

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.