Evidence map›Paper›PMID 32590438›Full record

ArticleAIDS (London, England)2020

A pragmatic approach to managing antiretroviral therapy-experienced patients diagnosed with HIV-associated cryptococcal meningitis: impact of antiretroviral therapy adherence and duration.

Melanie Alufandika, David S Lawrence, Timothée Boyer-Chammard, Cecilia Kanyama, Chiratidzo E Ndhlovu, Mosepele Mosepele, Lillian Tugume, David Meya, David R Boulware, Joshua Rhein and 10 more

Abstract read
In one paragraph

Article in AIDS (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Article
  3. Article
  4. Cryptococcal meningitis.Nature reviews. Disease primers · 2023
    Review
  5. Cryptococcal andOpen forum infectious diseases · 2022
    Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Melanie AlufandikaMalawi-Liverpool-Wellcome Trust Clinical Research Programme.
David S LawrenceDepartment of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK.
Timothée Boyer-ChammardMolecular Mycology Unit and National Reference Centre for Invasive Mycoses, UMR2000, CNRS, Institut Pasteur.
Cecilia KanyamaLilongwe Medical Relief Trust (UNC Project), Lilongwe, Malawi.
Chiratidzo E NdhlovuDepartment of Medicine, University of Zimbabwe College of Health Sciences, Parirenyatwa Hospital, Harare, Zimbabwe.
Mosepele MosepeleBotswana-Harvard AIDS Institute Partnership, Gaborone, Botswana.
Lillian TugumeInfectious Diseases Institute, College of Health Sciences, Makerere University, Kampala, Uganda.
David MeyaInfectious Diseases Institute, College of Health Sciences, Makerere University, Kampala, Uganda.
David R BoulwareUniversity of Minnesota, Minneapolis, USA.
Joshua RheinInfectious Diseases Institute, College of Health Sciences, Makerere University, Kampala, Uganda.
Conrad MuzooraMbarara University of Science and Technology, Mbarara, Uganda.
Nabila YoussoufDepartment of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK.
Síle F MolloyCentre for Global Health, Institute of Infection and Immunity, St George's University of London, London, UK.
Charlotte SchutzWellcome Centre for Infectious Diseases Research in Africa (CIDRI-Africa), Institute of Infectious Disease and Molecular Medicine.
Olivier LortholaryMolecular Mycology Unit and National Reference Centre for Invasive Mycoses, UMR2000, CNRS, Institut Pasteur.
Graeme MeintjesWellcome Centre for Infectious Diseases Research in Africa (CIDRI-Africa), Institute of Infectious Disease and Molecular Medicine.
Henry C MwandumbaMalawi-Liverpool-Wellcome Trust Clinical Research Programme.
Thomas S HarrisonCentre for Global Health, Institute of Infection and Immunity, St George's University of London, London, UK.
Joseph N JarvisDepartment of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK.
and the AMBITION-cm Study Group

Funding

Improving Diagnostics and Neurocognitive Outcomes in HIV/AIDS-related MeningitisR01NS086312 · NINDS · UNIVERSITY OF MINNESOTA · PI David R Boulware, David Bisagaya Meya · 2013 to 2026
$8.3M
Improving Outcomes of HIV-Associated Cryptococcosis in Resource-Limited SettingsK01TW010268 · FIC · UNIVERSITY OF MINNESOTA · PI RHEIN, JOSHUA R · 2016 to 2020
$703k
Department of Health RP-2017-08-ST2-012FIC NIH HHS K01 TW010268Medical Research Council MC_PC_MR/P006922/1NINDS NIH HHS R01 NS086312
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AIDS-Related Opportunistic InfectionsAntifungal AgentsAnti-Retroviral AgentsAntiretroviral Therapy, Highly ActiveHIV InfectionsHumansMedication AdherenceMeningitis, CryptococcalTreatment OutcomeAntifungal AgentsAnti-Retroviral Agents

Identifiers

PMID32590438
PMCPMC7473821

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.