Evidence map›Paper›PMID 32589955›Full record

ArticleCell2020

Role of Microbiota-Derived Bile Acids in Enteric Infections.

Casey M Theriot, William A Petri

Open access · bronzeAbstract readComment
In one paragraph

Article in Cell, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Microbiology spectrum · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Total glycosides contribute to the anti-diarrheal effects of Qiwei Baizhu PowderFrontiers in cellular and infection microbiology · 2022
    Article
  10. Article
  11. Article
  12. Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  13. Review
  14. Crosstalks Between Gut Microbiota andFrontiers in cellular and infection microbiology · 2020
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Casey M TheriotNorth Carolina State University, Raleigh, NC, USA.
William A PetriDepartment of Medicine, University of Virginia, PO Box 801340, Charlottesville, VA 22908-1340, USA. Electronic address: wap3g@virginia.edu.
North Carolina State University · USUniversity of Virginia · US

Funding

FIELD STUDIES OF IMMUNITY TO AMEBIASIS IN BANGLADESHR01AI043596 · NIAID · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI CAROL A GILCHRIST, William A Petri · 1998 to 2026
$7.7M
Role of Th17 in Severe and Recurrent C. difficile InfectionR01AI152477 · NIAID · UNIVERSITY OF VIRGINIA · PI PETRI, WILLIAM A, RAMAKRISHNAN, GIRIJA · 2020 to 2025
$7.1M
Role of Type 2 Immunity in Innate Protection from C. difficileR01AI124214 · NIAID · UNIVERSITY OF VIRGINIA · PI William A Petri · 2016 to 2026
$5.4M
Role of CREM in Amebic Colitis and Inflammatory Bowel DiseaseR37AI026649 · NIAID · UNIVERSITY OF VIRGINIA · PI William A Petri · 2018 to 2026
$5.0M
Targeted bacterial restoration of colonization resistance against C. difficileR35GM119438 · NIGMS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI THERIOT, CASEY MICHELLE · 2016 to 2020
$1.6M
NIAID NIH HHS R01 AI043596NIAID NIH HHS R01 AI124214NIAID NIH HHS R01 AI152477NIAID NIH HHS R37 AI026649NIGMS NIH HHS R35 GM119438
6 · The paper itself

Abstract

In this issue of Cell, Alavi et al. report that infection by Vibrio cholerae is blocked by gut microbiome-mediated hydrolysis of bile acids. Cholera therefore joins amebic dysentery and Clostridioides difficile colitis as enteric infections profoundly influenced by the microbiome's impact on bile acid metabolism.

Indexed as

CholeraGastrointestinal MicrobiomeMicrobiotaVibrio choleraeBile Acids and SaltsHumansBile Acids and Salts

Identifiers

PMID32589955
PMCPMC8162987
OpenAlexW3037148061

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.