Evidence map›Paper›PMID 32589832›Full record

ReviewACS synthetic biology2020

Robotic DNA Nanostructures.

Sami Nummelin, Boxuan Shen, Petteri Piskunen, Qing Liu, Mauri A Kostiainen, Veikko Linko

Abstract readReview
In one paragraph

Review in ACS synthetic biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed.

  1. Review
  2. Tunable Patterning of DNA Origami on Surfaces Using Steric Brushes.Angewandte Chemie (International ed. in English) · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Construction of a COChemistry (Weinheim an der Bergstrasse, Germany) · 2026
    Article
  7. Article
  8. Article
  9. Precise Regulation of Membrane Proteins: From Physical Technology to Biomolecular Strategy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  10. Article
  11. Dynamic Control of DNA Origami Self-Assembly by Transcriptional Modules.Journal of the American Chemical Society · 2026
    Article
  12. Article
  13. Advances in DNA- and RNA-Based Cancer Treatments.South Asian journal of cancer · 2025
    Article
  14. Article
  15. Signalling and social learning in swarms of robots.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2025
    Article
  16. Swarms can be rational.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2025
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sami NummelinBiohybrid Materials, Department of Bioproducts and Biosystems, Aalto University, 00076 Aalto, Finland.ORCID 0000-0003-2195-4818
Boxuan ShenBiohybrid Materials, Department of Bioproducts and Biosystems, Aalto University, 00076 Aalto, Finland.ORCID 0000-0002-1107-828X
Petteri PiskunenBiohybrid Materials, Department of Bioproducts and Biosystems, Aalto University, 00076 Aalto, Finland.ORCID 0000-0002-3142-3191
Qing LiuBiohybrid Materials, Department of Bioproducts and Biosystems, Aalto University, 00076 Aalto, Finland.ORCID 0000-0002-2251-3013
Mauri A KostiainenBiohybrid Materials, Department of Bioproducts and Biosystems, Aalto University, 00076 Aalto, Finland.ORCID 0000-0002-8282-2379
Veikko LinkoBiohybrid Materials, Department of Bioproducts and Biosystems, Aalto University, 00076 Aalto, Finland.ORCID 0000-0003-2762-1555

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over the past decade, DNA nanotechnology has spawned a broad variety of functional nanostructures tailored toward the enabled state at which applications are coming increasingly in view. One of the branches of these applications is in synthetic biology, where the intrinsic programmability of the DNA nanostructures may pave the way for smart task-specific molecular robotics. In brief, the synthesis of the user-defined artificial DNA nano-objects is based on employing DNA molecules with custom lengths and sequences as building materials that predictably assemble together by obeying Watson-Crick base pairing rules. The general workflow of creating DNA nanoshapes is getting more and more straightforward, and some objects can be designed automatically from the top down. The versatile DNA nano-objects can serve as synthetic tools at the interface with biology, for example, in therapeutics and diagnostics as dynamic logic-gated nanopills, light-, pH-, and thermally driven devices. Such diverse apparatuses can also serve as optical polarizers, sensors and capsules, autonomous cargo-sorting robots, rotary machines, precision measurement tools, as well as electric and magnetic-field directed robotic arms. In this review, we summarize the recent progress in robotic DNA nanostructures, mechanics, and their various implementations.

Indexed as

RoboticsBiosensing TechniquesDNADrug CarriersNanomedicineNanostructuresNanotechnologyDNADrug Carriersautonomous devicesbiomedicineDNA origamidynamic DNA nanotechnologyphotonics

Identifiers

PMID32589832
PMCPMC7467825

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.