Evidence map›Paper›PMID 32589704›Full record

ArticleCardiovascular research2021

'Social distancing' of the neuronal nitric oxide synthase from its adaptor protein causes arrhythmogenic trigger-substrate interactions in long QT syndrome.

Andrew Tieu, Fadi G Akar

Open access · bronzeAbstract readEditorialComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Cardiovascular research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 5 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Andrew TieuCardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Fadi G AkarDepartment of Internal Medicine, Section of Cardiovascular Medicine, Yale New Haven Hospital, New Haven, CT, USA.
Icahn School of Medicine at Mount Sinai · USYale University · US

Funding

Molecular Determinants of Mitochondrial Instability and ArrhythmiasR01HL137259 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI AKAR, FADI GABRIEL, O'ROURKE, BRIAN · 2017 to 2020
$2.0M
Mitochondrial fission in diabetes-related arrhythmiaR01HL149344 · NHLBI · YALE UNIVERSITY · PI AKAR, FADI GABRIEL · 2020 to 2023
$1.7M
NHLBI NIH HHS R01 HL137259NHLBI NIH HHS R01 HL149344
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Long QT SyndromePhysical DistancingAdaptor Proteins, Signal TransducingArrhythmias, CardiacHumansNitric Oxide Synthase Type IAdaptor Proteins, Signal TransducingNitric Oxide Synthase Type INOS1AP protein, humanNOS1 protein, human

Identifiers

PMID32589704
PMCPMC7820852
OpenAlexW3037939857

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.