Observational studyPloS one2020
Silicone Induced Granuloma of Breast Implant Capsule (SIGBIC) diagnosis: Breast Magnetic Resonance (BMR) sensitivity to detect silicone bleeding.
Observational study in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 25 citations in OpenAlex.
- Management of Asymptomatic Breast Implant Rupture in Older Adult Patients: A Scoping Review, Discussion, and Recommendations.Plastic and reconstructive surgery. Global open · 2026Article
- Confounding diagnosis of metastatic disease on FDG PET/CT due to cosmetic liquid silicone administration in breasts and gluteal regions with silicone migration to labia majora.Radiology case reports · 2025Article
- Dedicated Ultrasonography Versus Magnetic Resonance Imaging for Breast Implant Evaluation, Initial Study.Medical devices (Auckland, N.Z.) · 2025Article
- Silicone deposition and adverse pulmonary events secondary to breast implant rupture.Radiology case reports · 2025Article
- Silicone granuloma with intact breast implants: A case report.Radiology case reports · 2024Article
- Unraveling the Immune Web: Advances in SMI Capsular Fibrosis from Molecular Insights to Preclinical Breakthroughs.Biomolecules · 2024Review
- Why Is the Baker Classification Inadequate for Classifying Silicone Implant Fibrous Capsules?Cureus · 2024Article
- Breast Implant-Associated Tumors.Geburtshilfe und Frauenheilkunde · 2023Article
- Breast silicone implants' pericapsular impairment: current underdiagnosed status.Frontiers in surgery · 2023Review
- Management of Contralateral Breast and Axillary Nodes Silicone Migration after Implant Rupture.Plastic and reconstructive surgery. Global open · 2022Article
- Silicone exposure associated with breast papillary lesion: A case report.Radiology case reports · 2022Article
- Fundamentals of Breast Implant Illness and Device Imaging.International journal of inflammation · 2022Review
- The contradiction of breast implant illness.Gland surgery · 2021Article
- Side effects in breast implants related to radiotherapy in breast cancer reconstructive surgery.Technical innovations & patient support in radiation oncology · 2021Article
- The Breast Tumor Microenvironment: Could Silicone Breast Implant Elicit Breast Carcinoma?Breast cancer (Dove Medical Press) · 2021Article
- [Understanding Silicone Breast Implant-Associated Complications for Radiologists].Taehan Yongsang Uihakhoe chi · 2021Review
- Synchronous breast implant associated anaplastic large cell lymphoma (BIA-ALCL) and silicone induced granuloma of breast implant capsule (SIGBIC): What to learn.Radiology case reports · 2020Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the sensitivity (S) of BMRI to detect silicone gel bleeding in a prospective observational study, including consecutive patients referred for BMRI scan.
methodsFrom January 2017 to March 2018, we evaluated patients with breast implants referred for BMRI in a prospective observational study. For SIGBIC diagnosis, we adopted three new original imaging features: black drop signal; T2* hyper signal mass; and delayed contrast enhancement, considered as irrevocable signs to detect gel bleeding (GB). Histology confirmed the presence of a silicone corpuscle in breast implant capsular specimens. The accuracy of BMRI SIGBIC findings to predict GB was determined. We also compared SIGBIC diagnosis criteria to those features proposed by the BI-RADS léxicon, considered as equivocal findings.
results208 patients had SIGBIC diagnosis at BMRI, and the histology confirmed GB in all cases. There were no false-positive results. Compared to the BI-RADS equivocal findings (S = 0.74), SIGBIC criteria had better sensitivity for GB diagnosis.
conclusionSIGBIC diagnosis has high sensitivity to predict GB by the three irrevocable BMRI features described by the authors. We suppose GB is underdiagnosed in clinical practice by BI-RADS features. TRIAL CERTIFICATION: Study protocol: Plataforma Brasil CAAE: 77215317.0.0000.0072.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.