SynthesisPloS one2020
Postoperative mortality in patients on chronic dialysis following elective surgery: A systematic review and meta-analysis.
Synthesis in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.
- Morbidity after elective surgery in patients on chronic dialysis: a systematic review and meta-analysis.BMC nephrology · 2021Pooled it
- Application of Propofol Target-Controlled Infusion for Optimized Hemodynamic Status in ESRD Patients Receiving Arteriovenous Access Surgery: A Randomized Controlled Trial.Medicina (Kaunas, Lithuania) · 2022Trial
- Effect of Hemodiafiltration and Hemodialysis on Postoperative Mortality in Patients With Kidney Failure.Hemodialysis international. International Symposium on Home Hemodialysis · 2026Article
- Impact of residual kidney function on hemodynamic changes during induction of general anesthesia in hemodialysis patients: a retrospective observational study.Journal of anesthesia · 2026Article
- Relationship Between Timing of Hemodialysis and Procedure-Related Complications Following Endoscopy in Patients with End-Stage Renal Disease.Digestive diseases and sciences · 2025Article
- Preoperative Dialysis Dose and Postoperative Outcomes in Patients Receiving Maintenance Hemodialysis.Kidney360 · 2025Article
- Perioperative Management of the Patient Receiving Maintenance Hemodialysis.Anesthesiology · 2025Article
- Predicting Postoperative Cardiac Events and Mortality for People with Kidney Failure Having Noncardiac Surgery: An External Validation Study.Kidney360 · 2025Article
- Operative and nonoperative management of acute cholecystitis in patients on chronic kidney replacement therapy.Journal of hepato-biliary-pancreatic sciences · 2025Article
- Finding of a mass on the mitral valve in a patient on chronic dialysis.Radiology case reports · 2025Article
- Pancreaticoduodenectomy in a Hemodialysis Patient: First Report From Kazakhstan with a Brief Literature Review.International medical case reports journal · 2025Article
- Predicting In-Hospital Mortality in Patients with End-Stage Renal Disease Receiving Extracorporeal Membrane Oxygenation Therapy.Cardiorenal medicine · 2025Article
- Thoracoscopic minimally invasive surgical treatment with the same incisions in a patient with uremia complicated with large thymoma and right upper lobe lung cancer: a case report.Journal of cardiothoracic surgery · 2024Article
- Postoperative complications among dialysis-requiring patients undergoing splenectomy.Langenbeck's archives of surgery · 2024Article
- Perioperative Risk of Noncardiac Surgery in Patients With Asymptomatic Significant Aortic Stenosis: A 10-Year Retrospective Study.Journal of the American Heart Association · 2024Article
- Magnitude and associated factors of postoperative mortality among patients who underwent surgery in Ethiopia: systematic review and meta-analysis.Annals of medicine and surgery (2012) · 2024Review
- Prediction of major postoperative events after non-cardiac surgery for people with kidney failure: derivation and internal validation of risk models.BMC nephrology · 2023Article
- Article
- Major adverse cardiovascular events and all-cause mortality after emergency general surgery among kidney failure patients.BJS open · 2022Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
RATIONALE &
objectiveThe prognostic significance of dialysis-dependent end-stage kidney disease on postoperative mortality is unclear. This study aims to estimate the odds of postoperative mortality in patients receiving chronic dialysis undergoing elective surgery compared to patients with normal kidney function, and to examine the influence of comorbidities on the excess mortality risk.
methodsA systematic search of studies published up to January 2020 was conducted using MEDLINE, EMBASE and CENTRAL databases. Eligible studies reported postoperative 30-day or in-hospital mortality in chronic dialysis patients compared to patients with normal kidney function undergoing elective surgery. Two investigators independently reviewed all abstracts and performed risk of bias assessments using the Newcastle-Ottawa Scale. Quality of evidence was summarised in accordance with GRADE methodology (grading of recommendations, assessment, development and evaluation). Relative mortality risk estimates were obtained using random effects meta-analysis. Heterogeneity was explored using meta-regression. (PROSPERO CRD42017076565).
resultsForty-nine studies involving 41, 822 chronic dialysis and 10, 476, 321 non-dialysis patients undergoing elective surgery were included. Patients on chronic dialysis had a greatly increased postoperative mortality odds compared to patients with normal kidney function. The excess risk ranged from OR 10.8 (95%CI 7.3-15.9) following orthopaedic surgery to OR 4.0 (95%CI 3.2-4.9) after vascular surgery. Adjustment for age and comorbidity attenuated the excess odds but remained higher for patients on chronic dialysis, irrespective of surgical discipline. Meta-regression analysis demonstrated an inverse linear relationship between excess mortality risk and study-level mean age (slope -0.06; P = 0.001) and diabetes prevalence (slope -0.02; p = 0.001).
conclusionsPatients on chronic dialysis have an increased odds for postoperative mortality following elective surgery across all surgical disciplines. This relationship is consistent among all studies, with the excess postoperative mortality attributable to end-stage kidney disease and chronic dialysis treatment may be lower among older patients with diabetes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.