Evidence map›Paper›PMID 32589305›Full record

ArticleCancer science2020

Novel enhanced GFP-positive congenic inbred strain establishment and application of tumor-bearing nude mouse model.

Qing Lan, Yanming Chen, Chungang Dai, Shenggang Li, Xifeng Fei, Jun Dong, Yanhua Shen, Xingliang Dai, Zhaohui Lu, Bing Liu and 6 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Case Report: A novelFrontiers in oncology · 2022
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

Qing LanDepartment of Neurosurgery, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Yanming ChenDepartment of Neurosurgery, The Second Affiliated Hospital of Soochow University, Suzhou, China.ORCID https://orcid.org/0000-0001-9194-0580
Chungang DaiDepartment of Neurosurgery, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Shenggang LiDepartment of Neurosurgery, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Xifeng FeiDepartment of Neurosurgery, Suzhou Kowloon Hospital of Shanghai Jiaotong University School of Medicine, Suzhou, China.
Jun DongDepartment of Neurosurgery, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Yanhua ShenLaboratory Animal Center, Soochow University, Suzhou, China.
Xingliang DaiDepartment of Neurosurgery, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Zhaohui LuDepartment of Neurosurgery, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Bing LiuDepartment of Neurosurgery, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Qilong WangDepartment of Neurosurgery, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Haiyang WangDepartment of Neurosurgery, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Zhengyu ZhouLaboratory Animal Center, Soochow University, Suzhou, China.
Xiaoyan JiDepartment of Ophthalmology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Zhimin WangDepartment of Neurosurgery, Suzhou Kowloon Hospital of Shanghai Jiaotong University School of Medicine, Suzhou, China.
Qiang HuangDepartment of Neurosurgery, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Soochow University · CNKowloon Hospital · CNAnhui Medical University · CN

Funding

National Natural Science Foundation of China 81172400National Natural Science Foundation of China 81272799National Natural Science Foundation of China 81472739National Natural Science Foundation of China 81602183The Youth Medical Talent Foundation of Jiangsu QNRC2016217
6 · The paper itself

Abstract

Transgenic GFP gene mice are widely used. Given the unique advantages of immunodeficient animals in the field of oncology research, we aim to establish a nude mouse inbred strain that stably expresses enhanced GFP (EGFP) for use in transplanted tumor microenvironment (TME) research. Female C57BL/6-Tg(CAG-EGFP) mice were backcrossed with male BALB/c nude mice for 11 generations. The genotype and phenotype of novel inbred strain Foxn1

Indexed as

AnimalsBrainCell FusionCell Line, TumorCell Transformation, NeoplasticDisease Models, AnimalFemaleGliomaGreen Fluorescent ProteinsLuminescent ProteinsMaleMiceMice, Inbred BALB CMice, Inbred C57BLMice, NudeMice, TransgenicGreen Fluorescent ProteinsLuminescent ProteinsRed Fluorescent Proteincongenic inbred green fluorescent nude micedual-fluorescence tracing modelglioma stem cellsmalignant transformationtumor microenvironment

Identifiers

PMID32589305
PMCPMC7540977
OpenAlexW3038032100

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.