Evidence map›Paper›PMID 32589274›Full record

ArticleJournal of the American Geriatrics Society2020

Using Healthcare Data in Embedded Pragmatic Clinical Trials among People Living with Dementia and Their Caregivers: State of the Art.

Julie P W Bynum, David A Dorr, Julie Lima, Ellen P McCarthy, Ellen McCreedy, Richard Platt, V G Vinod Vydiswaran

Abstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Trial
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  15. Review
  16. Article
  17. Validation of Claims Algorithms to Identify Alzheimer's Disease and Related Dementias.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022
    Article
  18. Article
  19. Cognitive measures lacking in EHR prior to dementia or Alzheimer's disease diagnosis.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Julie P W BynumDepartment of Internal Medicine, Institute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor, Michigan, USA.
David A DorrDepartment of Medical Informatics & Clinical Epidemiology, Oregon Health & Science University, Portland, Oregon, USA.
Julie LimaCenter for Gerontology and Healthcare Research, School of Public Health, Brown University, Providence, Rhode Island, USA.
Ellen P McCarthyHinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Boston, Massachusetts, USA.
Ellen McCreedyCenter for Gerontology and Healthcare Research, School of Public Health, Brown University, Providence, Rhode Island, USA.ORCID 0000-0003-4063-8220
Richard PlattDepartment of Population Medicine, Harvard Pilgrim Health Care Institute, Harvard Medical School, Boston, Massachusetts, USA.
V G Vinod VydiswaranDepartment of Learning Health Sciences, University of Michigan, Ann Arbor, Michigan, USA.

Funding

Training Core (I)U54AG063546 · NIA · BROWN UNIVERSITY · PI Vincent Mor · 2019 to 2026
$125.9M
NIA NIH HHS U54 AG063546
6 · The paper itself

Abstract

Embedded pragmatic clinical trials (ePCTs) are embedded in healthcare systems as well as their data environments. For people living with dementia (PLWD), settings of care can be different from the general population and involve additional people whose information is also important. The ePCT designs have the opportunity to leverage data that becomes available through the normal delivery of care. They may be particularly valuable in Alzheimer's disease and Alzheimer's disease-related dementia (AD/ADRD), given the complexity of case identification and the diversity of care settings. Grounded in the objectives of the Data and Technical Core of the newly established National Institute on Aging Imbedded Pragmatic Alzheimer's Disease and AD-Related Dementias Clinical Trials Collaboratory (IMPACT Collaboratory), this article summarizes the state of the art in using existing data sources (eg, Medicare claims, electronic health records) in AD/ADRD ePCTs and approaches to integrating them in real-world settings. J Am Geriatr Soc 68:S49-S54, 2020.

Indexed as

Delivery of Health CareElectronic Health RecordsInsurance Claim ReviewOutcome and Process Assessment, Health CarePragmatic Clinical Trials as TopicCaregiversDementiaHumansMedicareUnited StatesAlzheimer's diseasedementiameasurementpragmatic trial

Identifiers

PMID32589274
PMCPMC7924260

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.