Evidence map›Paper›PMID 32589141›Full record

ArticleeLife2020

A Matlab-based toolbox for characterizing behavior of rodents engaged in string-pulling.

Samsoon Inayat, Surjeet Singh, Arashk Ghasroddashti, Qandeel, Pramuka Egodage, Ian Q Whishaw, Majid H Mohajerani

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 27 citations in OpenAlex.

  1. Cerebellar Purkinje cell firing reduction contributes to aging-related declining motor coordination in mice.Proceedings of the National Academy of Sciences of the United States of America · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Samsoon InayatCanadian Centre for Behavioural Neuroscience, University of Lethbridge, Lethbridge, Canada.ORCID 0000-0003-1966-7967
Surjeet SinghCanadian Centre for Behavioural Neuroscience, University of Lethbridge, Lethbridge, Canada.ORCID 0000-0002-4646-2089
Arashk GhasroddashtiCanadian Centre for Behavioural Neuroscience, University of Lethbridge, Lethbridge, Canada.
QandeelCanadian Centre for Behavioural Neuroscience, University of Lethbridge, Lethbridge, Canada.
Pramuka EgodageCanadian Centre for Behavioural Neuroscience, University of Lethbridge, Lethbridge, Canada.
Ian Q WhishawCanadian Centre for Behavioural Neuroscience, University of Lethbridge, Lethbridge, Canada.
Majid H MohajeraniCanadian Centre for Behavioural Neuroscience, University of Lethbridge, Lethbridge, Canada.ORCID 0000-0003-0964-2977
University of Lethbridge · CA

Funding

Alberta Alzheimer Research Program Grant PAZ15010Alberta Alzheimer Research Program Grant PAZ17010Alberta Innovates 43568Alzheimer Society of Canada 43674CIHR 390930Natural Sciences and Engineering Research Council of Canada 40352
6 · The paper itself

Abstract

String-pulling by rodents is a behavior in which animals make rhythmical body, head, and bilateral forearm as well as skilled hand movements to spontaneously reel in a string. Typical analysis includes kinematic assessment of hand movements done by manually annotating frames. Here, we describe a Matlab-based software that allows whole-body motion characterization using optical flow estimation, descriptive statistics, principal component, and independent component analyses as well as temporal measures of Fano factor, entropy, and Higuchi fractal dimension. Based on image-segmentation and heuristic algorithms for object tracking, the software also allows tracking of body, ears, nose, and forehands for estimation of kinematic parameters such as body length, body angle, head roll, head yaw, head pitch, and path and speed of hand movements. The utility of the task and software is demonstrated by characterizing postural and hand kinematic differences in string-pulling behavior of two strains of mice, C57BL/6 and Swiss Webster.

Indexed as

MovementOptic FlowAnimalsBiomechanical PhenomenaEntropyEthologyFractalsMaleMiceMice, Inbred C57BLMotor ActivitySoftwarebiomechanicshand kinematicsmatlab toolboxmouseneuroscienceratsensorimotor integrationstring-pullingswiss webster c57bl/6

Identifiers

PMID32589141
PMCPMC7347385
OpenAlexW3037319475

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.