Evidence map›Paper›PMID 32589111›Full record

ArticleJournal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc2020

Persistent infection and pancytopenia associated with ferret systemic coronaviral disease in a domestic ferret.

Danielle K Tarbert, Lisa L Bolin, Alison E Stout, Deanna M W Schaefer, Rebecca E Ruby, Julia Rodriguez-Ramos Fernandez, Gerald E Duhamel, Gary R Whittaker, Ricardo de Matos

Open access · bronzeAbstract read
In one paragraph

Article in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Danielle K TarbertCompanion Exotic Animal Medicine & Surgery Service, College of Veterinary Medicine, University of California-Davis, Davis, CA (Tarbert).ORCID https://orcid.org/0000-0003-4886-269X
Lisa L BolinCompanion Exotic Animal Medicine & Surgery Service, College of Veterinary Medicine, University of California-Davis, Davis, CA (Tarbert).
Alison E StoutCompanion Exotic Animal Medicine & Surgery Service, College of Veterinary Medicine, University of California-Davis, Davis, CA (Tarbert).
Deanna M W SchaeferCompanion Exotic Animal Medicine & Surgery Service, College of Veterinary Medicine, University of California-Davis, Davis, CA (Tarbert).
Rebecca E RubyCompanion Exotic Animal Medicine & Surgery Service, College of Veterinary Medicine, University of California-Davis, Davis, CA (Tarbert).
Julia Rodriguez-Ramos FernandezCompanion Exotic Animal Medicine & Surgery Service, College of Veterinary Medicine, University of California-Davis, Davis, CA (Tarbert).
Gerald E DuhamelCompanion Exotic Animal Medicine & Surgery Service, College of Veterinary Medicine, University of California-Davis, Davis, CA (Tarbert).
Gary R WhittakerCompanion Exotic Animal Medicine & Surgery Service, College of Veterinary Medicine, University of California-Davis, Davis, CA (Tarbert).
Ricardo de MatosCompanion Exotic Animal Medicine & Surgery Service, College of Veterinary Medicine, University of California-Davis, Davis, CA (Tarbert).
University of Kentucky · US

Funding

Graduate Training Program in Comparative MedicineT32OD011000 · OD · CORNELL UNIVERSITY · PI Amanda Marjorie DE MESTRE · 2012 to 2026
$5.7M
NIH HHS T32 OD011000
6 · The paper itself

Abstract

Ferret systemic coronaviral disease (FSCD) is a well-established cause of mortality in domestic ferrets. We describe herein novel findings in a case of FSCD that was diagnosed and medically managed following virus detection by immunohistochemical (IHC) staining of surgical biopsy samples. Hematologic changes in this ferret suggested spread of the virus to the bone marrow, which was confirmed by IHC staining of a postmortem sample. Genotyping of the virus indicated that the virus grouped with alphacoronaviruses and was most closely related to ferret enteric coronavirus (FRECV) MSU-2. Our clinical case demonstrates that a FRECV MSU-2-like ferret coronavirus associated previously with the enteric pathotype may cause systemic disease, including bone marrow involvement causing persistent pancytopenia.

Indexed as

AlphacoronavirusAnimalsCoronavirus InfectionsFerretsPancytopeniaalphacoronavirusbone marrowferret coronavirus MSU-2Mustela putorius furo

Identifiers

PMID32589111
PMCPMC7438646
OpenAlexW3037039212

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.