Evidence map›Paper›PMID 32588755›Full record

SynthesisPalliative medicine2020

Unmet device reprogramming needs at the end of life among patients with implantable cardioverter defibrillator: A systematic review and meta-analysis.

Valentina Gonzalez-Jaramillo, Piotr Sobanski, Jose A Calvache, Luisa F Arenas-Ochoa, Oscar H Franco, Lukas Hunziker, Steffen Eychmüller, Maud Maessen

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Palliative medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Valentina Gonzalez-JaramilloInstitute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland.ORCID 0000-0002-2470-7022
Piotr SobanskiPalliative Care Unit and Competence Centre, Department of Internal Medicine, Spital Schwyz, Schwyz, Switzerland.ORCID 0000-0002-2014-0356
Jose A CalvacheDepartment of Anesthesiology, Universidad del Cauca, Popayán, Colombia.
Luisa F Arenas-OchoaInstituto Colombiano del Dolor (INCODOL), Medellin, Colombia.
Oscar H FrancoInstitute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland.
Lukas HunzikerDepartment of Cardiology, Inselspital University Hospital Bern, Bern, Switzerland.
Steffen EychmüllerUniversity Center for Palliative Care, Inselspital University Hospital Bern, Bern, Switzerland.
Maud MaessenInstitute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUse of implantable cardioverter defibrillators is increasingly common. As patients approach the end of life, it is appropriate to deactivate the shock function.

aimTo assess the prevalence of implantable cardioverter defibrillator reprogramming to deactivate the shock function at the end of life and the prevalence of advance directives among this population.

designFollowing a previously established protocol available in PROSPERO, we performed a narrative synthesis of our findings and used the logit transformation method to perform our quantitative synthesis. DATA SOURCES: We searched seven bibliographic databases (Embase, Cochrane Central register of controlled Trials, Medline-Ovid, Web-of-Science, Scopus, PsychInfo, and CINAHL) and additional sources until April 2019.

resultsOf the references we identified, 14 were included. We found a pooled prevalence of implantable cardioverter defibrillator reprogramming at the end of life of 28% (95% confidence interval, 22%-36%) with higher reprogramming rates after the recommendations for managing the device at the end of life were published. Among patients with advance directives, the pooled prevalence of advance directives that explicitly mentioned the device was 1% (95% confidence interval, 1%-3%).

conclusionsThe prevalence of implantable cardioverter defibrillator reprogramming and advance directives that explicitly mentioned the device was very low. Study data suggested reprogramming decisions were made very late, after the patient experienced multiple shocks. Patient suffering could be ameliorated if physicians and other healthcare professionals adhere to clinical guidelines for the good management of the device at the end of life and include deactivating the shock function in the discussion that leads to the advance directive.

Indexed as

Defibrillators, ImplantableAdvance DirectivesDeathHumansadvanced care planningadvance directiveDefibrillatorsheart failureimplantablemeta-analysispalliative caresystematic reviewterminal care

Identifiers

PMID32588755
PMCPMC7388150

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.