Evidence map›Paper›PMID 32588551›Full record

ArticleThe FEBS journal2021

Loading messenger RNAs onto ribosomes in human mitochondria: lessons learned from a bacterial toxin.

Lukasz S Borowski, Roman J Szczesny

Abstract readComment
PubMed Publisher
In one paragraph

Article in The FEBS journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Lukasz S BorowskiInstitute of Biochemistry and Biophysics Polish Academy of Sciences, Warsaw, Poland.ORCID 0000-0003-3766-0726
Roman J SzczesnyInstitute of Biochemistry and Biophysics Polish Academy of Sciences, Warsaw, Poland.ORCID 0000-0002-0686-1632

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mitochondria are peculiar organelles because their function depends on genetic information that is present in two genomes: nuclear and mitochondrial. The expression of mitochondrially encoded information requires dedicated machinery. Many efforts have been made to identify this machinery and describe its relevant mechanisms. Recently, Bruni et al. reported a cellular model that they established to investigate the pathway for loading messenger RNAs onto ribosomes in human mitochondria. Their study revealed a role for monosome formation in the stability of mitochondrial mRNAs. Comment on: https://doi.org/10.1111/febs.15342.

Indexed as

Bacterial ToxinsMitochondrial RibosomesHumansMitochondriaRibosomesRNA, MessengerBacterial ToxinsRNA, Messengermitochondrial ribosomesmitochondrial RNA degradationmRNA loadingVapC20

Identifiers

PMID32588551

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.