Evidence map›Paper›PMID 32588371›Full record

ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2021

Left atrial appendage occlusion for ischemic stroke prevention in patients with non-valvular atrial fibrillation: clinical expert opinion and consensus statement for the Asian-Pacific region.

Edgar Tay, Biswajit Paul, Jason Sharp, Dennis Wang, Angus Shing Fung Chui, Prakash Kumar Hazra, Teguh Santoso, Bert Albers, Hans-Christoph Diener, Thorsten Lewalter and 1 more

Abstract readConsensus Statement
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In one paragraph

Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 7 countries.

Edgar TayNUHS Tower Block, Level 9 Cardiac Department, National University Hospital, National University Heart Centre Singapore, 1E Kent Ridge Road, Singapore, 119228, Singapore. edgartay1@gmail.com.
Biswajit PaulAMRI Hospitals, Kolkata, India.
Jason SharpSpecialist Cardiology, Wahroonga, Australia.
Dennis WangSpecialist Cardiology, Wahroonga, Australia.
Angus Shing Fung ChuiQueen Elizabeth Hospital, Hong Kong, Hong Kong.
Prakash Kumar HazraAMRI Hospitals, Kolkata, India.
Teguh SantosoMedistra Hospital, Jakarta, Indonesia.
Bert AlbersAlbers Clinical Evidence Consultancy, Woold, Winterswijk, The Netherlands.
Hans-Christoph DienerFaculty of Medicine, University Duisburg-Essen, Essen, Germany.
Thorsten LewalterPeter Osypka Heart Center, Munich, Germany.
Andrew WongRoyal Brisbane and Women's Hospital and University of Queensland, Brisbane, Australia.
AMRI Hospitals · INIndonesian Orthopaedic Association · IDNational University Heart Centre Singapore · SGOsypka (Germany) · DEQueen Elizabeth Hospital · CNRoyal Brisbane and Women's Hospital · AUStreekziekenhuis Koningin Beatrix · NLUniversity of Duisburg-Essen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo develop a consensus statement for left atrial appendage occlusion (LAAO) in Asian-Pacific patients with non-valvular atrial fibrillation (NVAF) at risk of ischemic stroke. The need for such a region-specific consensus was indicated by the relative paucity of clinical evidence for LAAO and oral anticoagulation therapy obtained in Asian-Pacific populations and the specific stroke and bleeding characteristics of this population.

methodsConsensus was developed by discussion and evaluation of available evidence and expert opinions during a 2-day meeting attended by clinical experts from the Asian-Pacific regions.

resultsThe consensus statement arrived at provides recommendations based on available evidence and expert opinions regarding LAAO in Asian-Pacific patients. Gaps in the evidence and other areas requiring further research were identified.

conclusionLAAO is an alternative device-based therapy in carefully selected patients with NVAF at risk of ischemic stroke. However, evidence for LAAO is primarily obtained from Caucasian populations, and data on LAAO in Asian-Pacific patients are scarce. While the present consensus statement addresses several therapy-related aspects based on careful interpretation of available evidence and expert opinions, other areas require additional evidence derived from Asian-Pacific populations.

Indexed as

Atrial AppendageAtrial FibrillationBrain IschemiaIschemic StrokeStrokeHumansTreatment OutcomeAsian-Pacific regionAtrial fibrillationConsensusIschemic stroke preventionLeft atrial appendage occlusion

Identifiers

PMID32588371
OpenAlexW3037113117

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.