Evidence map›Paper›PMID 32588239›Full record

ArticleCell biology and toxicology2020

Ion transport mechanisms for smoke inhalation-injured airway epithelial barrier.

Jianjun Chang, Zaixing Chen, Runzhen Zhao, Hong-Guang Nie, Hong-Long Ji

Open access · greenAbstract read
In one paragraph

Article in Cell biology and toxicology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Jianjun ChangDepartment of Cellular and Molecular Biology, University of Texas Health Science Center at Tyler, 11937 US Hwy 271, Tyler, TX, 75708, USA.
Zaixing ChenDepartment of Cellular and Molecular Biology, University of Texas Health Science Center at Tyler, 11937 US Hwy 271, Tyler, TX, 75708, USA.
Runzhen ZhaoDepartment of Cellular and Molecular Biology, University of Texas Health Science Center at Tyler, 11937 US Hwy 271, Tyler, TX, 75708, USA.
Hong-Guang NieDepartment of Stem Cells and Regenerative Medicine, College of Basic Medical Science, China Medical University, Shenyang, 110122, Liaoning, China. hgnie@cmu.edu.cn.
Hong-Long JiDepartment of Cellular and Molecular Biology, University of Texas Health Science Center at Tyler, 11937 US Hwy 271, Tyler, TX, 75708, USA. james.ji@uthct.edu.ORCID 0000-0002-3228-7144
The University of Texas Health Science Center at Tyler · USChina Medical University · CN

Funding

NOVEL PARACRINE MECHANISMS FOR CELL-BASED THERAPY OF INJURED LUNGSR01HL134828 · NHLBI · UNIVERSITY OF TEXAS HLTH CTR AT TYLER · PI JI, HONG-LONG · 2017 to 2025
$3.4M
NHLBI NIH HHS R01 HL134828
6 · The paper itself

Abstract

Smoke inhalation injury is the leading cause of death in firefighters and victims. Inhaled hot air and toxic smoke are the predominant hazards to the respiratory epithelium. We aimed to analyze the effects of thermal stress and smoke aldehyde on the permeability of the airway epithelial barrier. Transepithelial resistance (R

Indexed as

AcroleinAnimalsBronchiCells, CulturedCystic Fibrosis Transmembrane Conductance RegulatorElectric ImpedanceEpithelial CellsEpithelial Sodium ChannelsFemaleHot TemperatureHumansInhalation ExposureIon TransportMaleMembrane Transport ProteinsMice, Inbred C57BLAcroleinCFTR protein, humanCftr protein, mouseCystic Fibrosis Transmembrane Conductance RegulatorEpithelial Sodium ChannelsMembrane Transport ProteinsSmokeSodium-Potassium-Exchanging ATPaseTjp1 protein, mouseZonula Occludens-1 ProteinAcroleinIon transportThermal stressTight junctionsTracheal epithelial monolayers

Identifiers

PMID32588239
PMCPMC7669642
OpenAlexW3037681167

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.