SynthesisPediatric radiology2021
Whole-body magnetic resonance imaging in children - how and why? A systematic review.
Synthesis in Pediatric radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 44 citations in OpenAlex.
- Communicating incidental and reportable findings from research MRIs: considering factors beyond the findings in an underrepresented pediatric population.BMC medical research methodology · 2021Trial
- [Special aspects of magnetic resonance imaging of pediatric bone marrow].Radiologie (Heidelberg, Germany) · 2026Review
- Whole-body magnetic resonance imaging vs. positron emission tomography-computed tomography in pediatric oncology: enhancing diagnostic precision for solid tumors.Revista da Associacao Medica Brasileira (1992) · 2026Article
- Whole-body MRI in arthritis.Skeletal radiology · 2025Review
- Bacterial osteomyelitis in pediatric patients: a comprehensive review.Skeletal radiology · 2024Review
- Diagnostic Value of Whole-Body MRI in Pediatric Patients with Suspected Rheumatic Diseases.Medicina (Kaunas, Lithuania) · 2024Article
- Whole-Body MRI at Initial Presentation of Chronic Recurrent Multifocal Osteomyelitis, Juvenile Idiopathic Arthritis, Their Overlapping Syndrome, and Non-Specific Arthropathy.Journal of clinical medicine · 2024Article
- Machine Learning Algorithm: Texture Analysis in CNO and Application in Distinguishing CNO and Bone Marrow Growth-Related Changes on Whole-Body MRI.Diagnostics (Basel, Switzerland) · 2023Article
- Multifocal osteomyelitis in a child with sickle cell disease and review of the literature regarding best diagnostic approach.Clinical case reports · 2023Article
- Pediatric whole-body magnetic resonance imaging: comparison of STIR and T2 Dixon sequences in the detection and grading of high signal bone marrow changes.European radiology · 2023Article
- Improving protocols for whole-body magnetic resonance imaging: oncological and inflammatory applications.Pediatric radiology · 2023Review
- Comparison of the different imaging modalities used to image pediatric oncology patients: A COG diagnostic imaging committee/SPR oncology committee white paper.Pediatric blood & cancer · 2023Article
- Whole-body diffusion magnetic resonance imaging with simultaneous multi-slice excitation in children and adolescents.Pediatric radiology · 2023Article
- Whole-Body MRI in Musculoskeletal Oncology: A Comprehensive Review with Recommendations.Radiology. Imaging cancer · 2023Review
- Whole-body magnetic resonance imaging findings and patterns of chronic nonbacterial osteomyelitis in a series of Greek pediatric patients.Acta radiologica open · 2022Article
- Whole-body MRI in children aged 6-18 years. Reliability of identifying and grading high signal intensity changes within bone marrow.Pediatric radiology · 2022Article
- Screening of cancer predisposition syndromes.Pediatric radiology · 2022Review
- MRI in the Diagnosis and Treatment Response Assessment of Chronic Nonbacterial Osteomyelitis in Children and Adolescents.Current rheumatology reports · 2022Review
- Whole-body MRI in children: state of the art.BJR open · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Whole-body magnetic resonance imaging (MRI) is increasingly being used for a number of indications. Our aim was to review and describe indications and scan protocols for diagnostic value of whole-body MRI for multifocal disease in children and adolescents, we conducted a systematic search in Medline, Embase and Cochrane for all published papers until November 2018. Relevant subject headings and free text words were used for the following concepts: 1) whole-body, 2) magnetic resonance imaging and 3) child and/or adolescent. Included were papers in English with a relevant study design that reported on the use and/or findings from whole-body MRI examinations in children and adolescents. This review includes 54 of 1,609 papers identified from literature searches. Chronic nonbacterial osteomyelitis, lymphoma and metastasis were the most frequent indications for performing a whole-body MRI. The typical protocol included a coronal STIR (short tau inversion recovery) sequence with or without a coronal T1-weighted sequence. Numerous studies lacked sufficient data for calculating images resolution and only a few studies reported the acquired voxel volume, making it impossible for others to reproduce the protocol/images. Only a minority of the included papers assessed reliability tests and none of the studies documented whether the use of whole-body MRI affected mortality and/or morbidity. Our systematic review confirms significant variability of technique and the lack of proven validity of MRI findings. The information could potentially be used to boost attempts towards standardization of technique, reporting and guidelines development.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.