Evidence map›Paper›PMID 32587976›Full record

ArticlebioRxiv : the preprint server for biology2021

Cryo-EM structure of the SARS-CoV-2 3a ion channel in lipid nanodiscs.

David M Kern, Ben Sorum, Sonali S Mali, Christopher M Hoel, Savitha Sridharan, Jonathan P Remis, Daniel B Toso, Abhay Kotecha, Diana M Bautista, Stephen G Brohawn

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 111 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

David M KernDepartment of Molecular & Cell Biology, University of California Berkeley, Berkeley, California 94720, USA.
Ben SorumDepartment of Molecular & Cell Biology, University of California Berkeley, Berkeley, California 94720, USA.
Sonali S MaliDepartment of Molecular & Cell Biology, University of California Berkeley, Berkeley, California 94720, USA.
Christopher M HoelDepartment of Molecular & Cell Biology, University of California Berkeley, Berkeley, California 94720, USA.
Savitha SridharanDepartment of Molecular & Cell Biology, University of California Berkeley, Berkeley, California 94720, USA.
Jonathan P RemisCalifornia Institute for Quantitative Biology (QB3), University of California, Berkeley, CA 94720.
Daniel B TosoCalifornia Institute for Quantitative Biology (QB3), University of California, Berkeley, CA 94720.
Abhay KotechaMaterials and Structural Analysis Division, Thermo Fisher Scientific, Eindhoven, The Netherlands.
Diana M BautistaDepartment of Molecular & Cell Biology, University of California Berkeley, Berkeley, California 94720, USA.
Stephen G BrohawnDepartment of Molecular & Cell Biology, University of California Berkeley, Berkeley, California 94720, USA.
QB3 · USUniversity of California, Berkeley · USThermo Fisher Scientific (Netherlands) · NL

Funding

New approaches to understanding biological force sensationDP2GM123496 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI BROHAWN, STEPHEN GRAF · 2016 to 2016
$2.4M
Structural and mechanistic basis of cellular volume controlF32GM128263 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI KERN, DAVID MATTHEW · 2019 to 2020
$133k
NIGMS NIH HHS DP2 GM123496NIGMS NIH HHS F32 GM128263
6 · The paper itself

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the virus that causes the coronavirus disease 2019 (COVID-19). SARS-CoV-2 encodes three putative ion channels: E, 8a, and 3a

Identifiers

PMID32587976
PMCPMC7310636
OpenAlexW3036719193

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.