Evidence map›Paper›PMID 32587972›Full record

ArticlebioRxiv : the preprint server for biology2020

Characterization of the SARS-CoV-2 S Protein: Biophysical, Biochemical, Structural, and Antigenic Analysis.

Natalia G Herrera, Nicholas C Morano, Alev Celikgil, George I Georgiev, Ryan J Malonis, James H Lee, Karen Tong, Olivia Vergnolle, Aldo B Massimi, Laura Y Yen and 24 more

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 34 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

34 authors at 3 institutions in 1 country.

Natalia G HerreraDepartment of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, NY, 10461, USA.ORCID 0000-0003-1409-3554
Nicholas C MoranoDepartment of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, NY, 10461, USA.ORCID 0000-0002-8129-4033
Alev CelikgilDepartment of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, NY, 10461, USA.ORCID 0000-0001-8760-4496
George I GeorgievDepartment of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, NY, 10461, USA.
Ryan J MalonisDepartment of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, NY, 10461, USA.
James H LeeDepartment of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, NY, 10461, USA.
Karen TongDepartment of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, NY, 10461, USA.
Olivia VergnolleDepartment of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, NY, 10461, USA.
Aldo B MassimiDepartment of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, NY, 10461, USA.
Laura Y YenNational Resource for Molecular Microscopy, Simons Electron Microscopy Center, New York Structural Biology Center, 89 Convent Ave, New York, NY, 10027, USA.ORCID 0000-0002-4086-0895
Alex J NobleNational Resource for Molecular Microscopy, Simons Electron Microscopy Center, New York Structural Biology Center, 89 Convent Ave, New York, NY, 10027, USA.ORCID 0000-0001-8634-2279
Mykhailo KopylovNational Resource for Molecular Microscopy, Simons Electron Microscopy Center, New York Structural Biology Center, 89 Convent Ave, New York, NY, 10027, USA.ORCID 0000-0003-0188-9799
Jeffrey B BonannoDepartment of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, NY, 10461, USA.ORCID 0000-0003-0863-7826
Sarah C Garrett-ThomsonDepartment of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, NY, 10461, USA.
David B HayesIntl Solidarity of Scientists LLC, 9 Chuck Wagon Ln, Danbury, CT 06810, USA.ORCID 0000-0002-1133-3471
Robert H BortzDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, New York, NY 10461, USA.ORCID 0000-0003-1751-2152
Ariel S WirchnianskiDepartment of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, NY, 10461, USA.ORCID 0000-0002-3953-8954
Catalina FlorezDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, New York, NY 10461, USA.ORCID 0000-0002-0407-861X
Ethan LaudermilchDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, New York, NY 10461, USA.
Denise HaslwanterDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, New York, NY 10461, USA.
J Maximilian FelsDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, New York, NY 10461, USA.ORCID 0000-0003-1455-9318
M Eugenia DieterleDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, New York, NY 10461, USA.
Rohit K JangraDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, New York, NY 10461, USA.ORCID 0000-0002-3119-0869
Jason BarnhillDepartment of Chemistry and Life Science, United States Military Academy at West Point, West Point, NY 10996, USA.ORCID 0000-0001-9051-4256
Amanda MengottoDivision of Infectious Diseases, Department of Medicine, Albert Einstein College of Medicine and Montefiore Medical Center, New York, NY 10461, USA.ORCID 0000-0001-6383-422X
Duncan KimmelDivision of Infectious Diseases, Department of Medicine, Albert Einstein College of Medicine and Montefiore Medical Center, New York, NY 10461, USA.
Johanna P DailyDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, New York, NY 10461, USA.
Liise-Anne PirofskiDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, New York, NY 10461, USA.
Kartik ChandranDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, New York, NY 10461, USA.ORCID 0000-0003-0232-7077
Michael BrenowitzDepartment of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, NY, 10461, USA.ORCID 0000-0003-0048-1716
Scott J GarforthDepartment of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, NY, 10461, USA.ORCID 0000-0001-6281-4833
Edward T EngNational Resource for Molecular Microscopy, Simons Electron Microscopy Center, New York Structural Biology Center, 89 Convent Ave, New York, NY, 10027, USA.ORCID 0000-0002-8014-7269
Jonathan R LaiDepartment of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, NY, 10461, USA.ORCID 0000-0002-4863-0015
Steven C AlmoDepartment of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, NY, 10461, USA.ORCID 0000-0003-2591-5234
Albert Einstein College of Medicine · USNew York Structural Biology Center · USUnited States Military Academy · US

Funding

NCCAT: National Center for CryoEM Access and Training- Supplement for Windows 10 and FFIU24GM129539 · NIGMS · NEW YORK STRUCTURAL BIOLOGY CENTER · PI DE MARCO, ALEX, KIEFT, JEFFREY S · 2018 to 2023
$53.9M
ZWITTERION SURFACTANT DDMAB FOR IMPROV STABIL OF PROTEINP41RR001209 · NCRR · STANFORD UNIVERSITY · PI GONZALEZ, ANA M · 1985 to 2011
$38.9M
MEDICAL SCIENTIST TRAINING PROGRAMT32GM007288 · NIGMS · YESHIVA UNIVERSITY · PI AKABAS, MYLES H. · 1985 to 2022
$35.6M
Prometheus: A Platform for Rapid Development of Human Antibody-based Therapeutics and Prophylactics against Emerging Viral ThreatsU19AI142777 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI CHANDRAN, KARTIK · 2019 to 2023
$21.9M
TRD #3: An automated and streamlined pipeline for in-situ molecular microscopyP41GM103310 · NIGMS · SCRIPPS RESEARCH INSTITUTE, THE · PI KIEFT, JEFFREY S · 2012 to 2021
$14.7M
Dissecting the receptor-mediated infection mechanisms of hantavirusesR01AI132633 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI CHANDRAN, KARTIK · 2017 to 2021
$3.2M
Antibodies, B cells and resistance to human cryptococcosisR01AI143453 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI PIROFSKI, LIISE-ANNE · 2019 to 2024
$3.2M
Engineered, multispecific antibodies as broad anti-filovirus therapeuticsR01AI125462 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI LAI, JONATHAN R. · 2017 to 2020
$3.0M
Novel Strategies for Precision T-cell TherapiesR01CA198095 · NCI · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI ALMO, STEVEN C. · 2016 to 2020
$2.8M
Antibody therapy for pneumococcal diseaseR01AI123654 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI PIROFSKI, LIISE-ANNE · 2017 to 2021
$2.1M
How MeCP2 discriminates epigenetic marks is still a mysteryR01GM129350 · NIGMS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI BRENOWITZ, MICHAEL D. · 2018 to 2021
$1.3M
Plasmodium phospholipase A2s as potential novel drug targetsR21AI141367 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI DAILY, JOHANNA PATRICIA · 2019 to 2020
$459k
NCI NIH HHS R01 CA198095NCRR NIH HHS P41 RR001209NIAID NIH HHS R01 AI123654NIAID NIH HHS R01 AI125462NIAID NIH HHS R01 AI132633NIAID NIH HHS R01 AI143453NIAID NIH HHS R21 AI141367NIAID NIH HHS U19 AI142777NIGMS NIH HHS F32 GM128303NIGMS NIH HHS P41 GM103310NIGMS NIH HHS R01 GM129350NIGMS NIH HHS T32 GM007288NIGMS NIH HHS U24 GM129539
6 · The paper itself

Abstract

Coronavirus disease 2019 (

Identifiers

PMID32587972
PMCPMC7310628
OpenAlexW3034645203

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.