Evidence map›Paper›PMID 32587955›Full record

ArticleJournal of cellular immunology2020

Lung-targeted SERCA2a Gene Therapy: From Discovery to Therapeutic Application in Bleomycin-Induced Pulmonary Fibrosis.

Malik Bisserier, Lahouaria Hadri

Open access · goldAbstract read
In one paragraph

Article in Journal of cellular immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Progress in Respiratory Gene Therapy.Human gene therapy · 2022
    Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Malik BisserierCardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Lahouaria HadriCardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

Funding

TRAINING PROGRAM IN MOLECULAR AND CELLULAR CARDIOLOGYT32HL007824 · NHLBI · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI GELB, BRUCE D · 1995 to 2022
$8.6M
Interactions of SERCA2a and BMPRII in Vascular DiseaseR01HL133554 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI HADRI, LAHOUARIA · 2016 to 2020
$2.3M
American Heart Association-American Stroke Association 18IPA34170321NHLBI NIH HHS R01 HL133554NHLBI NIH HHS T32 HL007824
6 · The paper itself

Abstract

Idiopathic pulmonary fibrosis (IPF) is an interstitial lung disease characterized by an accumulation of scar tissue within the lungs and the common presence of usual interstitial pneumonia. Unfortunately, only a few FDA-approved therapeutic options are currently available for the treatment of IPF and IPF remains associated with poor prognosis. Therefore, the identification of new pharmacological targets and strategies are critical for the treatment of IPF. This commentary aims to further discuss the role of sarcoplasmic reticulum Ca

Indexed as

AAV1Gene TherapyLung FibrosisSERCA2a

Identifiers

PMID32587955
PMCPMC7316402
OpenAlexW3031361521

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.