Evidence map›Paper›PMID 32587933›Full record

ArticleJournal of the Endocrine Society2020

The Peripubertal Decline in

Stephanie A Roberts, Ana Paula Abreu, Victor M Navarro, Joy N Liang, Caroline A Maguire, Han Kyeol Kim, Rona S Carroll, Ursula B Kaiser

Open access · goldAbstract read
In one paragraph

Article in Journal of the Endocrine Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Genotype-Phenotype Correlations in Central Precocious Puberty Caused by MKRN3 Mutations.The Journal of clinical endocrinology and metabolism · 2021
    Article
  10. Makorin rings the kisspeptin bell to signal pubertal initiation.The Journal of clinical investigation · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Stephanie A RobertsDivision of Endocrinology, Boston Children's Hospital, Boston, Massachusetts.ORCID 0000-0002-2811-1322
Ana Paula AbreuDivision of Endocrinology, Diabetes and Hypertension, Brigham and Women's Hospital, Boston, Massachusetts.
Victor M NavarroDivision of Endocrinology, Diabetes and Hypertension, Brigham and Women's Hospital, Boston, Massachusetts.
Joy N LiangDivision of Endocrinology, Diabetes and Hypertension, Brigham and Women's Hospital, Boston, Massachusetts.
Caroline A MaguireDivision of Endocrinology, Diabetes and Hypertension, Brigham and Women's Hospital, Boston, Massachusetts.
Han Kyeol KimDivision of Endocrinology, Diabetes and Hypertension, Brigham and Women's Hospital, Boston, Massachusetts.
Rona S CarrollDivision of Endocrinology, Diabetes and Hypertension, Brigham and Women's Hospital, Boston, Massachusetts.
Ursula B KaiserDivision of Endocrinology, Diabetes and Hypertension, Brigham and Women's Hospital, Boston, Massachusetts.
Brigham and Women's Hospital · US

Funding

Hormones/Genes in Women's Health: From Bench to BedsideK12HD051959 · NICHD · BRIGHAM AND WOMEN'S HOSPITAL · PI GOLDSTEIN, JILL M, REXRODE, KATHRYN M · 2005 to 2023
$8.8M
Research in Development Endocrinology and MetabolismT32DK007699 · NIDDK · CHILDREN'S HOSPITAL BOSTON · PI JOEL N HIRSCHHORN · 1992 to 2026
$7.1M
TRAINING GRANT IN ACADEMIC ENDOCRINOLOGYT32DK007529 · NIDDK · BRIGHAM AND WOMEN'S HOSPITAL · PI Ursula B. Kaiser, Anand Vaidya · 1986 to 2026
$6.3M
Deciphering the functional role of MKRN3 in puberty and reproductionR01HD082314 · NICHD · BRIGHAM AND WOMEN'S HOSPITAL · PI Ursula B. Kaiser · 2015 to 2026
$5.7M
MKRN3 imprinting, regulation, and action in the control of pubertyR00HD091381 · NICHD · BRIGHAM AND WOMEN'S HOSPITAL · PI METZGER, ANA PAULA DE ABREU E SILVA · 2019 to 2021
$746k
Integrated analysis of genetic and epigenetic variants in central precocious pubertyR21HD098684 · NICHD · BRIGHAM AND WOMEN'S HOSPITAL · PI KAISER, URSULA B. · 2020 to 2021
$492k
NICHD NIH HHS K12 HD051959NICHD NIH HHS R00 HD091381NICHD NIH HHS R01 HD082314NICHD NIH HHS R21 HD098684NIDDK NIH HHS T32 DK007529NIDDK NIH HHS T32 DK007699
6 · The paper itself

Abstract

A critical body weight is necessary for pubertal development, an effect mediated in part by leptin. The potential regulation by leptin of

Indexed as

GnRHkisspeptinleptinMKRN3puberty

Identifiers

PMID32587933
PMCPMC7304661
OpenAlexW3026809290

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.