Evidence map›Paper›PMID 32587773›Full record

ArticleCancer biology & medicine2020

Heat shock protein 47 promotes tumor survival and therapy resistance by modulating AKT signaling

Yijye Chern, Peter Zhang, Hyelim Ju, Isabella T Tai

Open access · goldAbstract read
In one paragraph

Article in Cancer biology & medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yijye ChernDivision of Gastroenterology, Department of Medicine, University of British Columbia, Vancouver V6T 1Z4, Canada.
Peter ZhangDivision of Gastroenterology, Department of Medicine, University of British Columbia, Vancouver V6T 1Z4, Canada.
Hyelim JuDivision of Gastroenterology, Department of Medicine, University of British Columbia, Vancouver V6T 1Z4, Canada.
Isabella T TaiDivision of Gastroenterology, Department of Medicine, University of British Columbia, Vancouver V6T 1Z4, Canada.ORCID 0000-0001-9026-3194
University of British Columbia · CACanada's Michael Smith Genome Sciences Centre · CA

Funding

CIHR MOP-82881CIHR MSH-95344
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cell SurvivalAnimalsApoptosisCell Line, TumorColorectal NeoplasmsDatabases, FactualFemaleFluorouracilGene Expression Regulation, NeoplasticHSP47 Heat-Shock ProteinsHumansMiceMice, NudeNuclear ProteinsPhosphoprotein PhosphatasesPhosphorylationAKT1 protein, humanFluorouracilHSP47 Heat-Shock ProteinsNuclear ProteinsPHLPP1 protein, humanPhosphoprotein PhosphatasesProto-Oncogene Proteins c-aktSERPINH1 protein, humanAKTcolorectal cancerHSP47PHLPP1resistanc

Identifiers

PMID32587773
PMCPMC7309463
OpenAlexW3037704724

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.