Evidence map›Paper›PMID 32587610›Full record

ArticleNeural plasticity2020

An Age-Related Hearing Protection Locus on Chromosome 16 of BXD Strain Mice.

Qing Yin Zheng, Lihong Kui, Fuyi Xu, Tihua Zheng, Bo Li, Melinda McCarty, Zehua Sun, Aizheng Zhang, Luying Liu, Athena Starlard-Davenport and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neural plasticity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Qing Yin ZhengDepartment of Otolaryngology-Head and Neck Surgery, Case Western Reserve University, Cleveland, Ohio, USA.ORCID 0000-0002-5827-4106
Lihong KuiDepartment of Otolaryngology-Head and Neck Surgery, Case Western Reserve University, Cleveland, Ohio, USA.
Fuyi XuDepartment of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, TN 38106, USA.ORCID 0000-0002-5952-5771
Tihua ZhengHearing and Speech Rehabilitation Institute, College of Special Education, Binzhou Medical University, Yantai, China.
Bo LiHearing and Speech Rehabilitation Institute, College of Special Education, Binzhou Medical University, Yantai, China.
Melinda McCartyDepartment of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, TN 38106, USA.
Zehua SunDepartment of Otolaryngology-Head and Neck Surgery, Case Western Reserve University, Cleveland, Ohio, USA.
Aizheng ZhangDepartment of Otolaryngology-Head and Neck Surgery, Case Western Reserve University, Cleveland, Ohio, USA.
Luying LiuDepartment of Otolaryngology-Head and Neck Surgery, Case Western Reserve University, Cleveland, Ohio, USA.
Athena Starlard-DavenportDepartment of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, TN 38106, USA.
Ruben StepanyanDepartment of Otolaryngology-Head and Neck Surgery, Case Western Reserve University, Cleveland, Ohio, USA.
Bo Hua HuCenter for Hearing and Deafness, University at Buffalo, NY 14214, USA.
Lu LuDepartment of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, TN 38106, USA.ORCID 0000-0002-6174-3209
Binzhou Medical University · CNUniversity of Tennessee Health Science Center · USCase Western Reserve University · US

Funding

Deciphering the Usher I protein interactome using a geneticapproachR01DC015111 · NIDCD · CASE WESTERN RESERVE UNIVERSITY · PI ZHENG, QING Y · 2016 to 2020
$1.8M
Mechanotransduction and calcium regulation in cochlear hair cellsR01DC015016 · NIDCD · CASE WESTERN RESERVE UNIVERSITY · PI STEPANYAN, RUBEN · 2016 to 2020
$1.7M
Deciphering the Usher I protein interactome using a genetic approachR01DC009246 · NIDCD · CASE WESTERN RESERVE UNIVERSITY · PI ZHENG, QING Y · 2009 to 2013
$1.6M
NIDCD NIH HHS R01 DC009246NIDCD NIH HHS R01 DC015016NIDCD NIH HHS R01 DC015111
6 · The paper itself

Abstract

Inbred mouse models are widely used to study age-related hearing loss (AHL). Many genes associated with AHL have been mapped in a variety of strains. However, little is known about gene variants that have the converse function-protective genes that confer strong resistance to hearing loss. Previously, we reported that C57BL/6J (B6) and DBA/2J (D2) strains share a common hearing loss allele in

Indexed as

AllelesChromosomes, MammalianAnimalsAuditory ThresholdCadherinsEvoked Potentials, Auditory, Brain StemGenetic Predisposition to DiseaseGenotypeHearingHearing LossMicePhenotypeCadherinsCdh23 protein, mouse

Identifiers

PMID32587610
PMCPMC7298343
OpenAlexW3034015722

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.