ArticleMediators of inflammation2020
High Mean Platelet Volume Associates with In-Hospital Mortality in Severe Pneumonia Patients.
Article in Mediators of inflammation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Predictors of mortality in severe pneumonia patients: a systematic review and meta-analysis.Systematic reviews · 2024Pooled it
- HALP score and 30-day mortality: an observational analysis of clinical associations in Pneumonia.PeerJ · 2026Observational
- Analysis of influencing factors and construction of nomogram prediction model for pulmonary infection in patients with acute exacerbation of chronic obstructive pulmonary disease complicated with type II respiratory failure.Frontiers in medicine · 2026Article
- Advances in infection-immunity mechanisms and molecular regulatory networks in severe pneumonia-associated lung injury.Frontiers in immunology · 2026Review
- Development and validation of a clinical prediction model for in-hospital mortality of severe pneumonia based on machine learning.Frontiers in pharmacology · 2025Article
- Therapeutic outcomes and inflammatory modulation of inhaled N-acetylcysteine bronchoalveolar lavage in severe pneumonia.American journal of translational research · 2025Article
- Prognostic Significance of Thrombocytopenia and Mean Platelet Volume in COPD Patients with Acute Exacerbations in ICU Settings.Medical science monitor : international medical journal of experimental and clinical research · 2024Article
- Platelet Abnormalities in Children with Laboratory-Confirmed Influenza.Diagnostics (Basel, Switzerland) · 2023Article
- Establishment and Validation of the Risk Nomogram of Poor Prognosis in Patients with Severe Pulmonary Infection Complicated with Respiratory Failure.International journal of general medicine · 2023Article
- Mean platelet volume as a predictive biomarker for in-hospital mortality in patients receiving invasive mechanical ventilation.BMC pulmonary medicine · 2022Observational
- Article
- The author responds: Mean platelet volume may be an indicator of death in patients with Covid 19 pneumonia.The American journal of emergency medicine · 2022Article
- Relationship of platelet counts, platelet volumes, and Curb-65 scores in the prognosis of COVID-19 patients.The American journal of emergency medicine · 2022Article
- Mean platelet volume/platelet count ratio predicts severe pneumonia of COVID-19.Journal of clinical laboratory analysis · 2021Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough mean platelet volume (MPV) appears to be associated with poor outcome of pneumonia, the relationship between MPV and in-hospital mortality is unclear in severe pneumonia (SP) patients.
methodsIn this retrospective cohort study, 115 SP patients from June 1st, 2016, to September 29th, 2019, were included and divided into two groups. The primary outcome was in-hospital mortality. The receiver operating characteristic (ROC) curve was performed to assess the predictive ability for in-hospital mortality. Kaplan-Meier cumulative incidence curves were applied to observe the incidence of mortality. Multivariable Cox regression analyses were used to evaluate the hazard ratios (HRs). Besides, a formal test for interaction was investigated to analyze the relationship between MPV and sex.
resultsDuring the course of hospitalization, 63 cases of mortality were recorded. ROC analysis suggested that MPV had a modest power for predicting in-hospital mortality (AUC = 0.723, 95% CI: 0.628-0.818,
conclusionHigh MPV level is an independent risk factor for in-hospital mortality in patients with SP.
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