Evidence map›Paper›PMID 32587392›Full record

ArticleCommunications biology2020

Robust detection of oncometabolic aberrations by

Yasaman Barekatain, Victoria C Yan, Kenisha Arthur, Jeffrey J Ackroyd, Sunada Khadka, John De Groot, Jason T Huse, Florian L Muller

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Communications biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Live Metabolomics with NMR.Analytical chemistry · 2026
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Yasaman BarekatainDepartment of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, 77054, USA.
Victoria C YanDepartment of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, 77054, USA.
Kenisha ArthurDepartment of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, 77054, USA.
Jeffrey J AckroydDepartment of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, 77054, USA.
Sunada KhadkaDepartment of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, 77054, USA.
John De GrootDepartment of Neuro-Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
Jason T HuseDepartment of Pathology, University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
Florian L MullerDepartment of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, 77054, USA. aettius@aol.com.ORCID http://orcid.org/0000-0001-7568-2948
The University of Texas MD Anderson Cancer Center · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Fabien Delerue · 1985 to 2026
$290.8M
Tropism Enhanced Oncolytic Adenovirus for the Treatment of Brain TumorsP50CA127001 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Juan Fueyo · 2008 to 2026
$41.2M
Collateral Deletions Expose Targetable Metabolic Vulnerabilities in the PTEN locusR21CA226301 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI MULLER, FLORIAN · 2018 to 2019
$378k
NCI NIH HHS P30 CA016672NCI NIH HHS P50 CA127001NCI NIH HHS R21 CA226301
6 · The paper itself

Abstract

Magnetic resonance (MR) spectroscopy has potential to non-invasively detect metabolites of diagnostic significance for precision oncology. Yet, many metabolites have similar chemical shifts, yielding highly convoluted

Indexed as

AnimalsBiomarkers, TumorCarbon IsotopesCell Line, TumorFemaleGlioblastomaGluconatesGlutaratesHumansIsocitrate DehydrogenaseMagnetic Resonance SpectroscopyMetabolomicsMice, Inbred BALB CMutationPhosphogluconate DehydrogenaseSensitivity and Specificity6-phosphogluconic acidalpha-hydroxyglutarateBiomarkers, TumorCarbon-13Carbon IsotopesGluconatesGlutaratesIDH1 protein, humanIsocitrate DehydrogenasePhosphogluconate Dehydrogenase

Identifiers

PMID32587392
PMCPMC7316726
OpenAlexW3037755803

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.