Evidence map›Paper›PMID 32587088›Full record

ArticleThe Journal of biological chemistry2020

Flagellar targeting of an arginine kinase requires a conserved lipidated protein intraflagellar transport (LIFT) pathway in

Maneesha Pandey, Yameng Huang, Teck Kwang Lim, Qingsong Lin, Cynthia Y He

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Maneesha PandeyDepartment of Biological Sciences, National University of Singapore, Singapore.ORCID 0000-0003-1389-8668
Yameng HuangDepartment of Biological Sciences, National University of Singapore, Singapore.
Teck Kwang LimDepartment of Biological Sciences, National University of Singapore, Singapore.
Qingsong LinDepartment of Biological Sciences, National University of Singapore, Singapore.
Cynthia Y HeDepartment of Biological Sciences, National University of Singapore, Singapore dbshyc@nus.edu.sg.ORCID 0000-0001-5506-2661
National University of Singapore · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Both intraflagellar transport (IFT) and lipidated protein intraflagellar transport (LIFT) pathways are essential for cilia/flagella biogenesis, motility, and sensory functions. In the LIFT pathway, lipidated cargoes are transported into the cilia through the coordinated actions of cargo carrier proteins such as Unc119 or PDE6δ, as well as small GTPases Arl13b and Arl3 in the cilium. Our previous studies have revealed a single Arl13b ortholog in the evolutionarily divergent

Indexed as

Arginine KinaseBiological TransportFlagellaProtein BindingProtozoan ProteinsTrypanosoma brucei bruceiArginine KinaseProtozoan Proteinsarginine kinaseArl13Arl3ciliaflagellumflagellum/ciliumlipidated protein intraflagellar transport (LIFT)protein myristoylationprotein targetingproximity labelingsmall GTPaseTrypanosoma bruceiUnc119

Identifiers

PMID32587088
PMCPMC7415996
OpenAlexW3037237874

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.