Evidence map›Paper›PMID 32587063›Full record

ArticlemBio2020

Microwave-Generated Steam Decontamination of N95 Respirators Utilizing Universally Accessible Materials.

Katelyn E Zulauf, Alex B Green, Alex N Nguyen Ba, Tanush Jagdish, Dvir Reif, Robert Seeley, Alana Dale, James E Kirby

Open access · goldAbstract read
In one paragraph

Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 6 pooled it
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 6 syntheses or guidelines pooled it, 72 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. The COVID-19 pandemic and N95 masks: reusability and decontamination methods.Antimicrobial resistance and infection control · 2021
    Pooled it
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  7. Article
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  12. Mask disinfection using atmospheric pressure cold plasma.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2022
    Article
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  15. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Katelyn E Zulauf *Department of Pathology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
Alex B Green *Department of Pathology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
Alex N Nguyen BaDepartment of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts, USA.
Tanush JagdishProgram for Systems, Synthetic, and Quantitative Biology, Harvard University, Cambridge, Massachusetts, USA.
Dvir ReifDepartment of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts, USA.
Robert SeeleyEnvironmental Health and Safety Department, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
Alana DaleEnvironmental Health and Safety Department, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
James E KirbyDepartment of Pathology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA jekirby@bidmc.harvard.edu.ORCID 0000-0003-0392-4500
Beth Israel Deaconess Medical Center · USHarvard University · US

Funding

INFECTIOUS DISEASE AND BASIC MICROBIOLOGICAL MECHANISMST32AI007061 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI Marcia B Goldberg · 1985 to 2026
$12.1M
NIAID NIH HHS T32 AI007061
6 · The paper itself

Abstract

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has caused a severe, international shortage of N95 respirators, which are essential to protect health care providers from infection. Given the contemporary limitations of the supply chain, it is imperative to identify effective means of decontaminating, reusing, and thereby conserving N95 respirator stockpiles. To be effective, decontamination must result in sterilization of the N95 respirator without impairment of respirator filtration or user fit. Although numerous methods of N95 decontamination exist, none are universally accessible. In this work, we describe a microwave-generated steam decontamination protocol for N95 respirators for use in health care systems of all sizes, geographies, and means. Using widely available glass containers, mesh from commercial produce bags, a rubber band, and a 1,100-W commercially available microwave, we constructed an effective, standardized, and reproducible means of decontaminating N95 respirators. Employing this methodology against MS2 phage, a highly conservative surrogate for SARS-CoV-2 contamination, we report an average 6-log

Indexed as

MasksSteamBetacoronavirusCoronavirus InfectionsCOVID-19DecontaminationDisease Transmission, InfectiousDisinfectionEquipment ReuseFiltrationHumansMicrowavesPandemicsPneumonia, ViralReproducibility of ResultsSARS-CoV-2SteamCOVID-19disinfectionMS2 phageN95respiratorreuseSARS-CoV-2sterilization

Identifiers

PMID32587063
PMCPMC7317796
OpenAlexW3038097406

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.