Evidence map›Paper›PMID 32587022›Full record

ArticleScience (New York, N.Y.)2020

Arctic-adapted dogs emerged at the Pleistocene-Holocene transition.

Mikkel-Holger S Sinding, Shyam Gopalakrishnan, Jazmín Ramos-Madrigal, Marc de Manuel, Vladimir V Pitulko, Lukas Kuderna, Tatiana R Feuerborn, Laurent A F Frantz, Filipe G Vieira, Jonas Niemann and 25 more

Open access · greenAbstract read
In one paragraph

Article in Science (New York, N.Y.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
10.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 97 citations in OpenAlex.

  1. Article
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  10. Fine-scale recombination rates inferred using the canFam4 assembly are strongly correlated with previous maps of dog recombination.Mammalian genome : official journal of the International Mammalian Genome Society · 2025
    Article
  11. A 120-y time series of genomes reveals the consequences of closed breeding in German Shepherd Dogs.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  12. Imputation of ancient canid genomes reveals inbreeding history over the past 10,000 years.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  13. Absence ofVeterinary sciences · 2025
    Article
  14. Review
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  19. Ancient genomes reveal over two thousand years of dingo population structure.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

35 authors at 17 institutions in 12 countries.

Mikkel-Holger S Sinding *The GLOBE Institute, University of Copenhagen, Copenhagen, Denmark. mhssinding@gmail.com tomas.marques@upf.edu ajhansen@sund.ku.dk tgilbert@sund.ku.dk.ORCID 0000-0003-1371-219X
Shyam Gopalakrishnan *The GLOBE Institute, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-2004-6810
Jazmín Ramos-Madrigal *The GLOBE Institute, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-1661-7991
Marc de Manuel *Institute of Evolutionary Biology (UPF-CSIC), Barcelona, Spain.ORCID 0000-0002-1245-0127
Vladimir V Pitulko *Institute for the History of Material Culture, Russian Academy of Sciences, St. Petersburg, Russia.ORCID 0000-0001-5672-2756
Lukas KudernaInstitute of Evolutionary Biology (UPF-CSIC), Barcelona, Spain.ORCID 0000-0002-9992-9295
Tatiana R FeuerbornThe GLOBE Institute, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0003-1610-3402
Laurent A F FrantzThe Palaeogenomics and Bio-Archaeology Research Network, Research Laboratory for Archaeology and History of Art, University of Oxford, Oxford, UK.ORCID 0000-0001-8030-3885
Filipe G VieiraThe GLOBE Institute, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-8464-7770
Jonas NiemannThe GLOBE Institute, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-5153-100X
Jose A Samaniego CastruitaThe GLOBE Institute, University of Copenhagen, Copenhagen, Denmark.
Christian CarøeThe GLOBE Institute, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0001-9601-6768
Emilie U Andersen-RanbergThe Qimmeq Project, University of Greenland, Nuussuaq, Greenland.ORCID 0000-0002-3102-4844
Peter D JordanArctic Centre and Groningen Institute of Archaeology, University of Groningen, Netherlands.ORCID 0000-0002-2837-3920
Elena Y PavlovaArctic and Antarctic Research Institute, St. Petersburg, Russia.
Pavel A NikolskiyGeological Institute, Russian Academy of Sciences, Moscow, Russia.ORCID 0000-0001-6547-9890
Aleksei K KasparovInstitute for the History of Material Culture, Russian Academy of Sciences, St. Petersburg, Russia.ORCID 0000-0001-7761-9301
Varvara V IvanovaVNIIOkeangeologia Research Institute (The All-Russian Research Institute of Geology and Mineral Resources of the World Ocean), St. Petersburg, Russia.ORCID 0000-0002-7614-660X
Eske WillerslevThe GLOBE Institute, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-7081-6748
Pontus SkoglundDepartment of Genetics, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-3021-5913
Merete FredholmDepartment of Veterinary and Animal Sciences, University of Copenhagen, Frederiksberg C, Denmark.ORCID 0000-0002-3563-7648
Sanne Eline WennerbergMinistry of Fisheries, Hunting and Agriculture, Government of Greenland, Nuuk, Greenland.ORCID 0000-0003-1726-171X
Mads Peter Heide-JørgensenGreenland Institute of Natural Resources, Nuuk, Greenland.ORCID 0000-0003-4846-7622
Rune DietzDepartment of Bioscience, Arctic Research Centre, Aarhus University, Roskilde, Denmark.ORCID 0000-0001-9652-317X
Christian SonneThe Qimmeq Project, University of Greenland, Nuussuaq, Greenland.ORCID 0000-0001-5723-5263
Morten MeldgaardThe GLOBE Institute, University of Copenhagen, Copenhagen, Denmark.
Love DalénDepartment of Bioinformatics and Genetics, Swedish Museum of Natural History, Stockholm, Sweden.ORCID 0000-0001-8270-7613
Greger LarsonThe Palaeogenomics and Bio-Archaeology Research Network, Research Laboratory for Archaeology and History of Art, University of Oxford, Oxford, UK.ORCID 0000-0002-4092-0392
Bent PetersenThe GLOBE Institute, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-2472-8317
Thomas Sicheritz-PonténThe GLOBE Institute, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0001-6615-1141
Lutz BachmannNatural History Museum, University of Oslo, Oslo, Norway.ORCID 0000-0001-7451-2074
Øystein WiigNatural History Museum, University of Oslo, Oslo, Norway.ORCID 0000-0003-0395-5251
Tomas Marques-BonetInstitute of Evolutionary Biology (UPF-CSIC), Barcelona, Spain. mhssinding@gmail.com tomas.marques@upf.edu ajhansen@sund.ku.dk tgilbert@sund.ku.dk.ORCID 0000-0002-5597-3075
Anders J HansenThe GLOBE Institute, University of Copenhagen, Copenhagen, Denmark. mhssinding@gmail.com tomas.marques@upf.edu ajhansen@sund.ku.dk tgilbert@sund.ku.dk.ORCID 0000-0002-1890-2702
M Thomas P GilbertThe GLOBE Institute, University of Copenhagen, Copenhagen, Denmark. mhssinding@gmail.com tomas.marques@upf.edu ajhansen@sund.ku.dk tgilbert@sund.ku.dk.ORCID 0000-0002-5805-7195
University of Copenhagen · DKIlisimatusarfik · GLInstitut de Biologia Evolutiva · ESInstitute of History of Material Culture · RUUniversity of Oslo · NOAarhus University · DKAll Russian Research Institute of Geology and Mineral Resources of the World Ocean · RUArctic and Antarctic Research Institute · RUGeological Institute · RUGreenland Government · GLGrønlands Naturinstitut · GLHarvard University · USInstitució Catalana de Recerca i Estudis Avançats · ESInstitute of Archaeology · HUQueen Mary University of London · GBSwedish Museum of Natural History · SEUniversity of Oxford · GB

Funding

European Research Council 337574European Research Council 681396Wellcome Trust FC001595
6 · The paper itself

Abstract

Although sled dogs are one of the most specialized groups of dogs, their origin and evolution has received much less attention than many other dog groups. We applied a genomic approach to investigate their spatiotemporal emergence by sequencing the genomes of 10 modern Greenland sled dogs, an ~9500-year-old Siberian dog associated with archaeological evidence for sled technology, and an ~33,000-year-old Siberian wolf. We found noteworthy genetic similarity between the ancient dog and modern sled dogs. We detected gene flow from Pleistocene Siberian wolves, but not modern American wolves, to present-day sled dogs. The results indicate that the major ancestry of modern sled dogs traces back to Siberia, where sled dog-specific haplotypes of genes that potentially relate to Arctic adaptation were established by 9500 years ago.

Indexed as

Adaptation, PhysiologicalAnimalsApolipoproteinsArctic RegionsDogsFatty AcidsGenomeGreenlandHaplotypesMitochondrial Membrane Transport ProteinsSelective BreedingSequence Analysis, DNASiberiaTriglyceridesWolvesApolipoproteinsFatty AcidsMitochondrial Membrane Transport ProteinsTriglycerides

Identifiers

PMID32587022
PMCPMC7116267
OpenAlexW3037423625

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.