Evidence map›Paper›PMID 32586977›Full record

ArticleDevelopment (Cambridge, England)2020

Cortical distribution of GABAergic interneurons is determined by migration time and brain size.

Pietro Fazzari, Niall Mortimer, Odessa Yabut, Daniel Vogt, Ramon Pla

Open access · bronzeAbstract read
In one paragraph

Article in Development (Cambridge, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
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  10. Review
  11. Article
  12. Development, Diversity, and Death of MGE-Derived Cortical Interneurons.International journal of molecular sciences · 2021
    Review
  13. Development of Auditory Cortex Circuits.Journal of the Association for Research in Otolaryngology : JARO · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Pietro FazzariLaboratory of Cortical Circuits in Health and Disease, CIPF Centro de Investigación Príncipe Felipe, 46012 Valencia, Spain.ORCID 0000-0003-3457-9201
Niall MortimerDepartment of Psychiatry, Neuroscience Program and the Nina Ireland Laboratory of Developmental Neurobiology, University of California San Francisco, San Francisco, CA 94158, USA.ORCID 0000-0003-4608-2585
Odessa YabutDepartment of Neurology, University of California San Francisco, San Francisco, CA 94158, USA.ORCID 0000-0001-9991-0167
Daniel VogtDepartment of Psychiatry, Neuroscience Program and the Nina Ireland Laboratory of Developmental Neurobiology, University of California San Francisco, San Francisco, CA 94158, USA.ORCID 0000-0003-1876-5936
Ramon PlaDepartment of Psychiatry, Neuroscience Program and the Nina Ireland Laboratory of Developmental Neurobiology, University of California San Francisco, San Francisco, CA 94158, USA ramon.pla@uclm.es.ORCID 0000-0003-4115-149X
University of California, San Francisco · USCentro de Investigacion Principe Felipe · ESUniversitat Autònoma de Barcelona · ES

Funding

The Role of Suppressor of Fused in Neural Stem Cells and its Implications in TumorigenesisK01CA201068 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI YABUT, ODESSA · 2016 to 2019
$630k
NCI NIH HHS K01 CA201068
6 · The paper itself

Abstract

Cortical interneurons (CINs) originate in the ganglionic eminences (GEs) and migrate tangentially to the cortex guided by different attractive and repulsive cues. Once inside the cortex, the cellular and molecular mechanisms determining the migration of CINs along the rostrocaudal axis are less well understood. Here, we investigated the cortical distribution of CINs originating in the medial and caudal GEs at different time points. Using molecular and genetic labeling, we showed that, in the mouse, early- and late-born CINs (E12 versus E15) are differentially distributed along the rostrocaudal axis. Specifically, late-born CINs are preferentially enriched in cortical areas closer to their respective sites of origin in the medial or caudal GE. Surprisingly, our

Indexed as

AnimalsBrainCell LineageCell MovementCerebral CortexEmbryo, MammalianGABAergic Neuronsgamma-Aminobutyric AcidMiceMice, KnockoutOrgan SizeSomatosensory CortexThyroid Nuclear Factor 1gamma-Aminobutyric AcidNkx2-1 protein, mouseThyroid Nuclear Factor 1CortexGABAergic interneuronsMigrationNeuron

Identifiers

PMID32586977
PMCPMC7390637
OpenAlexW3038024060

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.