Evidence map›Paper›PMID 32586968›Full record

ArticleAJNR. American journal of neuroradiology2020

COVID-19 Is an Independent Risk Factor for Acute Ischemic Stroke.

P Belani, J Schefflein, S Kihira, B Rigney, B N Delman, K Mahmoudi, J Mocco, S Majidi, J Yeckley, A Aggarwal and 2 more

Open access · hybridAbstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 113 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
113citing papers in PubMed, 6 pooled it
14.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

113 citing papers in PubMed, 6 syntheses or guidelines pooled it, 212 citations in OpenAlex.

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  5. Stroke as a Neurological Complication of COVID-19: A Systematic Review and Meta-Analysis of Incidence, Outcomes and Predictors.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2021
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53 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

P BelaniFrom the Departments of Diagnostic, Molecular and Interventional Radiology (P.B., J.S., S.K., B.R., B.N.D., K.M., J.Y., A.A., D.L., A.H.D.) puneet.belani@mountsinai.org.ORCID 0000-0001-8618-8136
J ScheffleinFrom the Departments of Diagnostic, Molecular and Interventional Radiology (P.B., J.S., S.K., B.R., B.N.D., K.M., J.Y., A.A., D.L., A.H.D.).ORCID 0000-0002-3096-9643
S KihiraFrom the Departments of Diagnostic, Molecular and Interventional Radiology (P.B., J.S., S.K., B.R., B.N.D., K.M., J.Y., A.A., D.L., A.H.D.).ORCID 0000-0003-1001-8741
B RigneyFrom the Departments of Diagnostic, Molecular and Interventional Radiology (P.B., J.S., S.K., B.R., B.N.D., K.M., J.Y., A.A., D.L., A.H.D.).ORCID 0000-0002-5886-1423
B N DelmanFrom the Departments of Diagnostic, Molecular and Interventional Radiology (P.B., J.S., S.K., B.R., B.N.D., K.M., J.Y., A.A., D.L., A.H.D.).ORCID 0000-0002-9792-8942
K MahmoudiFrom the Departments of Diagnostic, Molecular and Interventional Radiology (P.B., J.S., S.K., B.R., B.N.D., K.M., J.Y., A.A., D.L., A.H.D.).ORCID 0000-0002-2002-5710
J MoccoNeurosurgery (J.M., S.M.), Icahn School of Medicine at Mount Sinai, New York, New York.ORCID 0000-0001-5489-2524
S MajidiNeurosurgery (J.M., S.M.), Icahn School of Medicine at Mount Sinai, New York, New York.ORCID 0000-0003-2971-6216
J YeckleyFrom the Departments of Diagnostic, Molecular and Interventional Radiology (P.B., J.S., S.K., B.R., B.N.D., K.M., J.Y., A.A., D.L., A.H.D.).ORCID 0000-0001-8195-3310
A AggarwalFrom the Departments of Diagnostic, Molecular and Interventional Radiology (P.B., J.S., S.K., B.R., B.N.D., K.M., J.Y., A.A., D.L., A.H.D.).ORCID 0000-0002-9562-6457
D LeftonFrom the Departments of Diagnostic, Molecular and Interventional Radiology (P.B., J.S., S.K., B.R., B.N.D., K.M., J.Y., A.A., D.L., A.H.D.).ORCID 0000-0001-6051-3746
A H DoshiFrom the Departments of Diagnostic, Molecular and Interventional Radiology (P.B., J.S., S.K., B.R., B.N.D., K.M., J.Y., A.A., D.L., A.H.D.).ORCID 0000-0002-2507-436X
Society of Interventional Radiology · USIcahn School of Medicine at Mount Sinai · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeCoronavirus disease 2019 (COVID-19) is an active worldwide pandemic with diverse complications. Stroke as a presentation has not been strongly associated with COVID-19. The authors aimed to retrospectively review a link between COVID-19 and acute stroke. MATERIALS AND

methodsWe conducted a retrospective case-control study of 41 cases and 82 control subjects matched by age, sex, and risk factors. Cases were patients who underwent stroke alert imaging with confirmed acute stroke on imaging between March 16 and April 5, 2020, at 6 hospitals across New York City. Control subjects were those who underwent stroke alertimaging during the same timeframe without imaging evidence of acute infarction. Data pertaining to diagnosis of COVID-19 infection, patient demographics, and risk factors were collected. A univariate analysis was performed to assess the covariate effect of risk factors and COVID-19 status on stroke imaging with positive findings.

resultsThe mean age for cases and controls was 65.5 ± 15.3 years and 68.8 ± 13.2 years, respectively. Of patients with acute ischemic stroke, 46.3% had COVID-19 infection compared with 18.3% of controls (

conclusionsWe demonstrated that COVID-19 infection is significantly associated with imaging confirmation of acute ischemic stroke, and patients with COVID-19 should undergo more aggressive monitoring for stroke.

Indexed as

BetacoronavirusAgedAged, 80 and overBrain IschemiaCoronavirus InfectionsCOVID-19FemaleHumansMaleMiddle AgedPandemicsPneumonia, ViralRetrospective StudiesRisk FactorsSARS-CoV-2Stroke

Identifiers

PMID32586968
PMCPMC7658882
OpenAlexW3037968992

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.