Evidence map›Paper›PMID 32586956›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Convergent evolution of conserved mitochondrial pathways underlies repeated adaptation to extreme environments.

Ryan Greenway, Nick Barts, Chathurika Henpita, Anthony P Brown, Lenin Arias Rodriguez, Carlos M Rodríguez Peña, Sabine Arndt, Gigi Y Lau, Michael P Murphy, Lei Wu and 4 more

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 83 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Ancestral gene flow shaped the singular origin of the Amazon molly.bioRxiv : the preprint server for biology · 2026
    Article
  4. The genetic foundations of convergent traits.Nature reviews. Genetics · 2026
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 5 countries.

Ryan GreenwayDivision of Biology, Kansas State University, Manhattan, KS 66506.ORCID 0000-0002-7182-7932
Nick BartsDivision of Biology, Kansas State University, Manhattan, KS 66506.ORCID 0000-0003-4641-3647
Chathurika HenpitaDepartment of Integrative Biology, Oklahoma State University, Stillwater, OK 74078.ORCID 0000-0002-7610-1380
Anthony P BrownSchool of Biological Sciences, Washington State University, Pullman, WA 99163.ORCID 0000-0001-6100-2470
Lenin Arias RodriguezDivisión Académica de Ciencias Biológicas, Universidad Juárez Autónoma de Tabasco, Villahermosa, Tabasco, 86150, Mexico.ORCID 0000-0002-8025-5569
Carlos M Rodríguez PeñaInstituto de Investigaciones Botánicas y Zoológicas, Universidad Autónoma de Santo Domingo, Santo Domingo, 10105, Dominican Republic.ORCID 0000-0003-0472-1350
Sabine ArndtMedical Research Council - Mitochondrial Biology Unit, University of Cambridge, Cambridge, CB2 0XY, United Kingdom.
Gigi Y LauDepartment of Biosciences, University of Oslo, 0315 Oslo, Norway.
Michael P MurphyMedical Research Council - Mitochondrial Biology Unit, University of Cambridge, Cambridge, CB2 0XY, United Kingdom.
Lei WuDepartment of Nutritional Sciences, Oklahoma State University, Stillwater, OK 74078.
Dingbo LinDepartment of Nutritional Sciences, Oklahoma State University, Stillwater, OK 74078.ORCID 0000-0002-7441-8210
Michael ToblerDivision of Biology, Kansas State University, Manhattan, KS 66506; tobler@ksu.edu joanna.l.kelley@wsu.edu jennifer.shaw@pcom.edu.ORCID 0000-0002-0326-0890
Joanna L KelleySchool of Biological Sciences, Washington State University, Pullman, WA 99163; tobler@ksu.edu joanna.l.kelley@wsu.edu jennifer.shaw@pcom.edu.ORCID 0000-0002-7731-605X
Jennifer H ShawDepartment of Integrative Biology, Oklahoma State University, Stillwater, OK 74078; tobler@ksu.edu joanna.l.kelley@wsu.edu jennifer.shaw@pcom.edu.ORCID 0000-0003-0670-9291
Oklahoma State University · USKansas State University · USUniversity of Cambridge · GBWashington State University · USUniversidad Autónoma de Santo Domingo · DOUniversidad Juárez Autónoma de Tabasco · MXUniversity of Oslo · NO

Funding

Medical Research Council MC_U105663142Medical Research Council MC_UU_00015/3Wellcome Trust 110158/Z/15/ZWellcome Trust 110159/Z/15/Z
6 · The paper itself

Abstract

Extreme environments test the limits of life; yet, some organisms thrive in harsh conditions. Extremophile lineages inspire questions about how organisms can tolerate physiochemical stressors and whether the repeated colonization of extreme environments is facilitated by predictable and repeatable evolutionary innovations. We identified the mechanistic basis underlying convergent evolution of tolerance to hydrogen sulfide (H

Indexed as

Evolution, MolecularAdaptation, PhysiologicalAnimalsEcosystemExtreme EnvironmentsGenomeHydrogen SulfideMitochondriaPhylogenyPoeciliaHydrogen Sulfideadaptive evolutioncomparative physiologyecological genomicshydrogen sulfidephylogenetic comparative analysis

Identifiers

PMID32586956
PMCPMC7368198
OpenAlexW3037827193

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.