ArticleNeurology2020
Patterns of motor recovery and structural neuroplasticity after basal ganglia infarcts.
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Article in Neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.
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27citing papers in PubMed, 3 pooled it
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Who cites it
27 citing papers in PubMed, 3 syntheses or guidelines pooled it, 38 citations in OpenAlex.
- Neuronal substrates of motor impairment after subcortical ischemic stroke: a functional neuroimaging meta-analysis.Brain structure & function · 2025Pooled it
- The prevalence and anatomy of recurrent artery of Heubner: a meta analysis with neurosurgical considerations.Acta neurochirurgica · 2024Pooled it
- Cortical Thickness of Brain Areas Beyond Stroke Lesions and Sensory-Motor Recovery: A Systematic Review.Frontiers in neuroscience · 2021Pooled it
- Common and unique structural plasticity after left and right hemisphere stroke.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021Trial
- The Adolescent Microbiome-Gut-Brain Axis: Development, Mechanisms, and Translational Perspectives.Nutrients · 2026Review
- Cortical functional hierarchy disruption following subcortical stroke.BMC medicine · 2026Article
- Neurorehabilitation Combining Acupuncture and Conventional Rehabilitation in the Acute Ischemic Stroke: Evidence From Multimodal MRI.Neural plasticity · 2026Article
- A Resource for Exploring Regional Diversity in the Male Rat Brain Synaptic Proteome.Scientific data · 2025Article
- Somatosensory-Thalamic Functional Dysconnectivity Associated With Poststroke Motor Function Rehabilitation: A Resting-State fMRI Study.Brain and behavior · 2025Article
- Brain changes in stroke patients during rehabilitation: a longitudinal study.Frontiers in neuroscience · 2025Article
- Early acupuncture intervention strongly associates with improved swallowing recovery in post-stroke dysphagia: a multicenter real-world cohort study.Frontiers in neurology · 2025Article
- Exploring the Relationship between Abnormal Communication Efficiency of Cerebral Cortex and Multiple Cognitive Functions in Mild Subcortical Stroke: A Resting-State fMRI Study.Brain sciences · 2024Article
- Compensatory increase in ipsilesional supplementary motor area and premotor connectivity is associated with greater gait impairments: a personalized fMRI analysis in chronic stroke.Frontiers in human neuroscience · 2024Article
- Location matters: altered interhemispheric homotopic connectivity in post-stroke dyskinesia.Frontiers in neurology · 2024Article
- Assessing the cortical microstructure in contralesional sensorimotor areas after stroke.Brain communications · 2024Article
- Dynamic reorganization of cortical structure in multi-domain regions after capsular and pontine stroke.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023Observational
- Changes in Resting-State Neural Activity and Nerve Fibres in Ischaemic Stroke Patients with Hemiplegia.Brain topography · 2023Article
- Cortical structural changes after subcortical stroke: Patterns and correlates.Human brain mapping · 2023Observational
- Aberrant dynamic Functional-Structural connectivity coupling of Large-scale brain networks in poststroke motor dysfunction.NeuroImage. Clinical · 2023Article
- Selectively disrupted sensorimotor circuits in chronic stroke with hand dysfunction.CNS neuroscience & therapeutics · 2022Article
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Authors and funding
15 authors at 1 institution in 3 countries.
Hesheng LiuFrom the Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology (H.L., X.P., L.D., H.W., J. Li, N.L., R.P., D.W.), Massachusetts General Hospital, Harvard Medical School, Charlestown; Beijing Institute for Brain Disorders (H.L.), Departments of Radiology (M.Z., Y.S., D.R., J. Lu) and Nuclear Medicine (J. Lu), Xuanwu Hospital, and Department of Neurology, Beijing Friendship Hospital (Y.G.), Capital Medical University; Liaoyuan Hospital of Traditional Chinese Medicine (L.W.); Department of Neurosurgery (Y.L.), First Affiliated Hospital, Fujian Medical University, Fuzhou, China; Department of Neuroscience (H.L., X.P.), Medical University of South Carolina, Charleston; Department of Radiology (X.P.), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan; Changchun University of Chinese Medicine (H.W.); and Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics (M.Z., Y.S., D.R., J. Lu), China.
Xiaolong PengFrom the Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology (H.L., X.P., L.D., H.W., J. Li, N.L., R.P., D.W.), Massachusetts General Hospital, Harvard Medical School, Charlestown; Beijing Institute for Brain Disorders (H.L.), Departments of Radiology (M.Z., Y.S., D.R., J. Lu) and Nuclear Medicine (J. Lu), Xuanwu Hospital, and Department of Neurology, Beijing Friendship Hospital (Y.G.), Capital Medical University; Liaoyuan Hospital of Traditional Chinese Medicine (L.W.); Department of Neurosurgery (Y.L.), First Affiliated Hospital, Fujian Medical University, Fuzhou, China; Department of Neuroscience (H.L., X.P.), Medical University of South Carolina, Charleston; Department of Radiology (X.P.), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan; Changchun University of Chinese Medicine (H.W.); and Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics (M.Z., Y.S., D.R., J. Lu), China.
Louisa DahmaniFrom the Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology (H.L., X.P., L.D., H.W., J. Li, N.L., R.P., D.W.), Massachusetts General Hospital, Harvard Medical School, Charlestown; Beijing Institute for Brain Disorders (H.L.), Departments of Radiology (M.Z., Y.S., D.R., J. Lu) and Nuclear Medicine (J. Lu), Xuanwu Hospital, and Department of Neurology, Beijing Friendship Hospital (Y.G.), Capital Medical University; Liaoyuan Hospital of Traditional Chinese Medicine (L.W.); Department of Neurosurgery (Y.L.), First Affiliated Hospital, Fujian Medical University, Fuzhou, China; Department of Neuroscience (H.L., X.P.), Medical University of South Carolina, Charleston; Department of Radiology (X.P.), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan; Changchun University of Chinese Medicine (H.W.); and Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics (M.Z., Y.S., D.R., J. Lu), China.
Hongfeng WangFrom the Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology (H.L., X.P., L.D., H.W., J. Li, N.L., R.P., D.W.), Massachusetts General Hospital, Harvard Medical School, Charlestown; Beijing Institute for Brain Disorders (H.L.), Departments of Radiology (M.Z., Y.S., D.R., J. Lu) and Nuclear Medicine (J. Lu), Xuanwu Hospital, and Department of Neurology, Beijing Friendship Hospital (Y.G.), Capital Medical University; Liaoyuan Hospital of Traditional Chinese Medicine (L.W.); Department of Neurosurgery (Y.L.), First Affiliated Hospital, Fujian Medical University, Fuzhou, China; Department of Neuroscience (H.L., X.P.), Medical University of South Carolina, Charleston; Department of Radiology (X.P.), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan; Changchun University of Chinese Medicine (H.W.); and Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics (M.Z., Y.S., D.R., J. Lu), China.
Miao ZhangFrom the Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology (H.L., X.P., L.D., H.W., J. Li, N.L., R.P., D.W.), Massachusetts General Hospital, Harvard Medical School, Charlestown; Beijing Institute for Brain Disorders (H.L.), Departments of Radiology (M.Z., Y.S., D.R., J. Lu) and Nuclear Medicine (J. Lu), Xuanwu Hospital, and Department of Neurology, Beijing Friendship Hospital (Y.G.), Capital Medical University; Liaoyuan Hospital of Traditional Chinese Medicine (L.W.); Department of Neurosurgery (Y.L.), First Affiliated Hospital, Fujian Medical University, Fuzhou, China; Department of Neuroscience (H.L., X.P.), Medical University of South Carolina, Charleston; Department of Radiology (X.P.), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan; Changchun University of Chinese Medicine (H.W.); and Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics (M.Z., Y.S., D.R., J. Lu), China.
Yi ShanFrom the Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology (H.L., X.P., L.D., H.W., J. Li, N.L., R.P., D.W.), Massachusetts General Hospital, Harvard Medical School, Charlestown; Beijing Institute for Brain Disorders (H.L.), Departments of Radiology (M.Z., Y.S., D.R., J. Lu) and Nuclear Medicine (J. Lu), Xuanwu Hospital, and Department of Neurology, Beijing Friendship Hospital (Y.G.), Capital Medical University; Liaoyuan Hospital of Traditional Chinese Medicine (L.W.); Department of Neurosurgery (Y.L.), First Affiliated Hospital, Fujian Medical University, Fuzhou, China; Department of Neuroscience (H.L., X.P.), Medical University of South Carolina, Charleston; Department of Radiology (X.P.), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan; Changchun University of Chinese Medicine (H.W.); and Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics (M.Z., Y.S., D.R., J. Lu), China.
Dongdong RongFrom the Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology (H.L., X.P., L.D., H.W., J. Li, N.L., R.P., D.W.), Massachusetts General Hospital, Harvard Medical School, Charlestown; Beijing Institute for Brain Disorders (H.L.), Departments of Radiology (M.Z., Y.S., D.R., J. Lu) and Nuclear Medicine (J. Lu), Xuanwu Hospital, and Department of Neurology, Beijing Friendship Hospital (Y.G.), Capital Medical University; Liaoyuan Hospital of Traditional Chinese Medicine (L.W.); Department of Neurosurgery (Y.L.), First Affiliated Hospital, Fujian Medical University, Fuzhou, China; Department of Neuroscience (H.L., X.P.), Medical University of South Carolina, Charleston; Department of Radiology (X.P.), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan; Changchun University of Chinese Medicine (H.W.); and Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics (M.Z., Y.S., D.R., J. Lu), China.
Yanjun GuoFrom the Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology (H.L., X.P., L.D., H.W., J. Li, N.L., R.P., D.W.), Massachusetts General Hospital, Harvard Medical School, Charlestown; Beijing Institute for Brain Disorders (H.L.), Departments of Radiology (M.Z., Y.S., D.R., J. Lu) and Nuclear Medicine (J. Lu), Xuanwu Hospital, and Department of Neurology, Beijing Friendship Hospital (Y.G.), Capital Medical University; Liaoyuan Hospital of Traditional Chinese Medicine (L.W.); Department of Neurosurgery (Y.L.), First Affiliated Hospital, Fujian Medical University, Fuzhou, China; Department of Neuroscience (H.L., X.P.), Medical University of South Carolina, Charleston; Department of Radiology (X.P.), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan; Changchun University of Chinese Medicine (H.W.); and Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics (M.Z., Y.S., D.R., J. Lu), China.
Junchao LiFrom the Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology (H.L., X.P., L.D., H.W., J. Li, N.L., R.P., D.W.), Massachusetts General Hospital, Harvard Medical School, Charlestown; Beijing Institute for Brain Disorders (H.L.), Departments of Radiology (M.Z., Y.S., D.R., J. Lu) and Nuclear Medicine (J. Lu), Xuanwu Hospital, and Department of Neurology, Beijing Friendship Hospital (Y.G.), Capital Medical University; Liaoyuan Hospital of Traditional Chinese Medicine (L.W.); Department of Neurosurgery (Y.L.), First Affiliated Hospital, Fujian Medical University, Fuzhou, China; Department of Neuroscience (H.L., X.P.), Medical University of South Carolina, Charleston; Department of Radiology (X.P.), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan; Changchun University of Chinese Medicine (H.W.); and Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics (M.Z., Y.S., D.R., J. Lu), China.
Nianlin LiFrom the Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology (H.L., X.P., L.D., H.W., J. Li, N.L., R.P., D.W.), Massachusetts General Hospital, Harvard Medical School, Charlestown; Beijing Institute for Brain Disorders (H.L.), Departments of Radiology (M.Z., Y.S., D.R., J. Lu) and Nuclear Medicine (J. Lu), Xuanwu Hospital, and Department of Neurology, Beijing Friendship Hospital (Y.G.), Capital Medical University; Liaoyuan Hospital of Traditional Chinese Medicine (L.W.); Department of Neurosurgery (Y.L.), First Affiliated Hospital, Fujian Medical University, Fuzhou, China; Department of Neuroscience (H.L., X.P.), Medical University of South Carolina, Charleston; Department of Radiology (X.P.), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan; Changchun University of Chinese Medicine (H.W.); and Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics (M.Z., Y.S., D.R., J. Lu), China.
Long WangFrom the Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology (H.L., X.P., L.D., H.W., J. Li, N.L., R.P., D.W.), Massachusetts General Hospital, Harvard Medical School, Charlestown; Beijing Institute for Brain Disorders (H.L.), Departments of Radiology (M.Z., Y.S., D.R., J. Lu) and Nuclear Medicine (J. Lu), Xuanwu Hospital, and Department of Neurology, Beijing Friendship Hospital (Y.G.), Capital Medical University; Liaoyuan Hospital of Traditional Chinese Medicine (L.W.); Department of Neurosurgery (Y.L.), First Affiliated Hospital, Fujian Medical University, Fuzhou, China; Department of Neuroscience (H.L., X.P.), Medical University of South Carolina, Charleston; Department of Radiology (X.P.), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan; Changchun University of Chinese Medicine (H.W.); and Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics (M.Z., Y.S., D.R., J. Lu), China.
Yuanxiang LinFrom the Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology (H.L., X.P., L.D., H.W., J. Li, N.L., R.P., D.W.), Massachusetts General Hospital, Harvard Medical School, Charlestown; Beijing Institute for Brain Disorders (H.L.), Departments of Radiology (M.Z., Y.S., D.R., J. Lu) and Nuclear Medicine (J. Lu), Xuanwu Hospital, and Department of Neurology, Beijing Friendship Hospital (Y.G.), Capital Medical University; Liaoyuan Hospital of Traditional Chinese Medicine (L.W.); Department of Neurosurgery (Y.L.), First Affiliated Hospital, Fujian Medical University, Fuzhou, China; Department of Neuroscience (H.L., X.P.), Medical University of South Carolina, Charleston; Department of Radiology (X.P.), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan; Changchun University of Chinese Medicine (H.W.); and Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics (M.Z., Y.S., D.R., J. Lu), China.
Ruiqi PanFrom the Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology (H.L., X.P., L.D., H.W., J. Li, N.L., R.P., D.W.), Massachusetts General Hospital, Harvard Medical School, Charlestown; Beijing Institute for Brain Disorders (H.L.), Departments of Radiology (M.Z., Y.S., D.R., J. Lu) and Nuclear Medicine (J. Lu), Xuanwu Hospital, and Department of Neurology, Beijing Friendship Hospital (Y.G.), Capital Medical University; Liaoyuan Hospital of Traditional Chinese Medicine (L.W.); Department of Neurosurgery (Y.L.), First Affiliated Hospital, Fujian Medical University, Fuzhou, China; Department of Neuroscience (H.L., X.P.), Medical University of South Carolina, Charleston; Department of Radiology (X.P.), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan; Changchun University of Chinese Medicine (H.W.); and Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics (M.Z., Y.S., D.R., J. Lu), China.
Jie LuFrom the Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology (H.L., X.P., L.D., H.W., J. Li, N.L., R.P., D.W.), Massachusetts General Hospital, Harvard Medical School, Charlestown; Beijing Institute for Brain Disorders (H.L.), Departments of Radiology (M.Z., Y.S., D.R., J. Lu) and Nuclear Medicine (J. Lu), Xuanwu Hospital, and Department of Neurology, Beijing Friendship Hospital (Y.G.), Capital Medical University; Liaoyuan Hospital of Traditional Chinese Medicine (L.W.); Department of Neurosurgery (Y.L.), First Affiliated Hospital, Fujian Medical University, Fuzhou, China; Department of Neuroscience (H.L., X.P.), Medical University of South Carolina, Charleston; Department of Radiology (X.P.), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan; Changchun University of Chinese Medicine (H.W.); and Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics (M.Z., Y.S., D.R., J. Lu), China. imaginglu@hotmail.com.ORCID 0000-0003-0425-3921
Danhong WangFrom the Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology (H.L., X.P., L.D., H.W., J. Li, N.L., R.P., D.W.), Massachusetts General Hospital, Harvard Medical School, Charlestown; Beijing Institute for Brain Disorders (H.L.), Departments of Radiology (M.Z., Y.S., D.R., J. Lu) and Nuclear Medicine (J. Lu), Xuanwu Hospital, and Department of Neurology, Beijing Friendship Hospital (Y.G.), Capital Medical University; Liaoyuan Hospital of Traditional Chinese Medicine (L.W.); Department of Neurosurgery (Y.L.), First Affiliated Hospital, Fujian Medical University, Fuzhou, China; Department of Neuroscience (H.L., X.P.), Medical University of South Carolina, Charleston; Department of Radiology (X.P.), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan; Changchun University of Chinese Medicine (H.W.); and Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics (M.Z., Y.S., D.R., J. Lu), China.
Fujian Medical University · CN
Funding
The neural network of OCD, linking NHP and human studiesP50MH106435 · NIMH · UNIVERSITY OF ROCHESTER · PI Suzanne N Haber · 2015 to 2026
$28.9MTreating Depression and Enhancing Locomotor Recovery Post-strokeP20GM109040 · NIGMS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI KAUTZ, STEVEN A. · 2014 to 2024
$23.5MTechniques DevelopmentP2CHD086844 · NICHD · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI KAUTZ, STEVEN A. · 2015 to 2024
$12.7MMapping the intrinsic functional organization of auditory cortex in individual subjects using 7T MRIR01DC017991 · NIDCD · MASSACHUSETTS GENERAL HOSPITAL · PI AHVENINEN, JYRKI · 2019 to 2023
$4.0MTranslating The Individualized Functional Connectome To Surgical PlanningR01NS091604 · NINDS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI LIU, HESHENG · 2015 to 2019
$2.1MUnderstanding Functional Connectivity Abnormalities In Individual Patients with PsychosisK01MH111802 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI WANG, DANHONG · 2017 to 2021
$931kNICHD NIH HHS P2C HD086844NIDCD NIH HHS R01 DC017991NIGMS NIH HHS P20 GM109040NIMH NIH HHS K01 MH111802NIMH NIH HHS P50 MH106435NINDS NIH HHS R01 NS091604
Abstract
objectiveTo elucidate the timeframe and spatial patterns of cortical reorganization after different stroke-induced basal ganglia lesions, we measured cortical thickness at 5 time points over a 6-month period. We hypothesized that cortical reorganization would occur very early and that, along with motor recovery, it would vary based on the stroke lesion site.
methodsThirty-three patients with unilateral basal ganglia stroke and 23 healthy control participants underwent MRI scanning and behavioral testing. To further decrease heterogeneity, we split patients into 2 groups according to whether or not the lesions mainly affect the striatal motor network as defined by resting-state functional connectivity. A priori measures included cortical thickness and motor outcome, as assessed with the Fugl-Meyer scale.
resultsWithin 14 days poststroke, cortical thickness already increased in widespread brain areas (
conclusionsOur findings underline the importance of assessing patients early and of considering individual differences, as patterns of cortical reorganization differ substantially depending on the precise location of damage and occur very soon after stroke. A better understanding of the macrostructural brain changes following stroke and their relationship with recovery may inform individualized treatment strategies.
Indexed as
Neuronal PlasticityRecovery of FunctionAdultBasal Ganglia Cerebrovascular DiseaseBrain InfarctionCase-Control StudiesCerebral CortexFemaleFunctional NeuroimagingHumansLongitudinal StudiesMagnetic Resonance ImagingMaleMiddle AgedNeostriatumNeural Pathways
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