Evidence map›Paper›PMID 32586890›Full record

ArticleGenetics2020

Site-Specific Recombination with Inverted Target Sites: A Cautionary Tale of Dicentric and Acentric Chromosomes.

Simon W A Titen, Makenna T B Johnson, Mario Capecchi, Kent G Golic

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Simon W A TitenEccles Institute of Human Genetics, School of Medicine, University of Utah, Salt Lake City, Utah, 84112.
Makenna T B JohnsonSchool of Biological Sciences, University of Utah, Salt Lake City, Utah, 84112.
Mario CapecchiEccles Institute of Human Genetics, School of Medicine, University of Utah, Salt Lake City, Utah, 84112.
Kent G GolicSchool of Biological Sciences, University of Utah, Salt Lake City, Utah, 84112 golic@biology.utah.edu.ORCID 0000-0002-0495-0084
University of Utah · US

Funding

TRAINING PROGRAM IN GENETICST32GM007464 · NIGMS · UNIVERSITY OF UTAH · PI GRUNWALD, DAVID J., STANFIELD, GILLIAN · 1985 to 2020
$6.1M
Responses to Telomere LossR01GM065604 · NIGMS · UNIVERSITY OF UTAH · PI GOLIC, KENT G · 2001 to 2019
$4.9M
Targeting of Genes in the Mammalian GenomeR01CA210165 · NCI · UNIVERSITY OF UTAH · PI CAPECCHI, MARIO R · 2016 to 2020
$2.4M
From Defective Microglia to Cortical Activity and Pathological BehaviorR01MH093595 · NIMH · UNIVERSITY OF UTAH · PI CAPECCHI, MARIO R · 2011 to 2015
$2.1M
NCI NIH HHS R01 CA210165NIGMS NIH HHS R01 GM065604NIGMS NIH HHS T32 GM007464NIMH NIH HHS R01 MH093595
6 · The paper itself

Abstract

Site-specific recombinases are widely used tools for analysis of genetics, development, and cell biology, and many schemes have been devised to alter gene expression by recombinase-mediated DNA rearrangements. Because the

Indexed as

Recombination, GeneticAnimalsChromosomesDNA NucleotidyltransferasesDrosophila melanogasterFemaleIntegrasesMaleMiceCre recombinaseDNA NucleotidyltransferasesIntegrasesSite-specific recombinaseCredicentricDrosophilaFLPFRTloxmouserecombinasesister chromatidsite-specific recombination

Identifiers

PMID32586890
PMCPMC7404229
OpenAlexW3037150690

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.