Evidence map›Paper›PMID 32586885›Full record

ReviewThe European respiratory journal2020

Epidemic and pandemic viral infections: impact on tuberculosis and the lung: A consensus by the World Association for Infectious Diseases and Immunological Disorders (WAidid), Global Tuberculosis Network (GTN), and members of the European Society of Clinical Microbiology and Infectious Diseases Study Group for Mycobacterial Infections (ESGMYC).

Catherine Wei Min Ong, Giovanni Battista Migliori, Mario Raviglione, Gavin MacGregor-Skinner, Giovanni Sotgiu, Jan-Willem Alffenaar, Simon Tiberi, Cornelia Adlhoch, Tonino Alonzi, Sophia Archuleta and 37 more

Open access · bronzeAbstract readConsensus StatementReview
In one paragraph

Review in The European respiratory journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed, 3 pooled it
2.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

85 citing papers in PubMed, 3 syntheses or guidelines pooled it, 143 citations in OpenAlex.

  1. Pooled it
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  3. Pathology of TB/COVID-19 Co-Infection: The phantom menace.Tuberculosis (Edinburgh, Scotland) · 2021
    Pooled it
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  12. Frontiers in immunology · 2025
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25 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

47 authors at 20 institutions in 13 countries.

Catherine Wei Min OngDept of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.ORCID 0000-0003-1103-0451
Giovanni Battista MiglioriServizio di Epidemiologia Clinica delle Malattie Respiratorie, Istituti Clinici Scientifici Maugeri IRCCS, Tradate, Italy delia.goletti@inmi.it giovannibattista.migliori@icsmaugeri.it.ORCID 0000-0002-2597-574X
Mario RaviglioneCentre for Multidisciplinary Research in Health Science, University of Milan, Milan, Italy.
Gavin MacGregor-SkinnerDept of Public Health Sciences, Penn State College of Medicine, Hershey, PA, USA.
Giovanni SotgiuClinical Epidemiology and Medical Statistics Unit, Dept of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari, Italy.ORCID 0000-0002-1600-4474
Jan-Willem AlffenaarSydney Pharmacy School, University of Sydney, Sydney, Australia.
Simon TiberiBlizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.ORCID 0000-0002-0738-4276
Cornelia AdlhochPublic Health Emergency Team, European Centre for Disease Prevention and Control, Stockholm, Sweden.ORCID 0000-0002-8842-0469
Tonino AlonziTranslational Research Unit, Epidemiology and Preclinical Research Dept, "L. Spallanzani" National Institute for Infectious Diseases (INMI), IRCCS, Rome, Italy.
Sophia ArchuletaDept of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Sergio BrusinPublic Health Emergency Team, European Centre for Disease Prevention and Control, Stockholm, Sweden.
Emmanuelle CambauAP-HP-Lariboisiere, Bacteriologie, Laboratory Associated to the National Reference Centre for Mycobacteria, IAME UMR1137, INSERM, University of Paris, Paris, France.
Maria Rosaria CapobianchiLaboratory of Virology, Epidemiology and Preclinical Research Dept, "L. Spallanzani" National Institute for Infectious Diseases (INMI), IRCCS, Rome, Italy.
Concetta CastillettiLaboratory of Virology, Epidemiology and Preclinical Research Dept, "L. Spallanzani" National Institute for Infectious Diseases (INMI), IRCCS, Rome, Italy.
Rosella CentisServizio di Epidemiologia Clinica delle Malattie Respiratorie, Istituti Clinici Scientifici Maugeri IRCCS, Tradate, Italy.ORCID 0000-0002-8551-3598
Daniela M CirilloEmerging Bacterial Pathogens Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.ORCID 0000-0001-6415-1535
Lia D'AmbrosioPublic Health Consulting Group, Lugano, Switzerland.ORCID 0000-0002-7000-5777
Giovanni DeloguUniversità Cattolica Sacro Cuore, Roma, Italy.
Susanna M R EspositoPediatric Clinic, Pietro Barilla Children's Hospital, University of Parma, Parma, Italy.
Jose FigueroaNational Health Service, London, UK.
Jon S FriedlandSt George's, University of London, London, UK.ORCID 0000-0001-7789-9649
Benjamin Choon Heng HoTuberculosis Control Unit, Dept of Respiratory and Critical Care Medicine, Tan Tock Seng Hospital, Singapore.ORCID 0000-0002-9506-3738
Giuseppe IppolitoScientific Direction, "L. Spallanzani" National Institute for Infectious Diseases (INMI), IRCCS, Rome, Italy.
Mateja JankovicSchool of Medicine, University of Zagreb and Clinic for Respiratory Diseases, University Hospital Center Zagreb, Zagreb, Croatia.ORCID 0000-0002-0171-764X
Hannah Yejin KimSydney Pharmacy School, University of Sydney, Sydney, Australia.
Senia Rosales KlintzPublic Health Emergency Team, European Centre for Disease Prevention and Control, Stockholm, Sweden.
Csaba KödmönPublic Health Emergency Team, European Centre for Disease Prevention and Control, Stockholm, Sweden.
Eleonora LalleLaboratory of Virology, Epidemiology and Preclinical Research Dept, "L. Spallanzani" National Institute for Infectious Diseases (INMI), IRCCS, Rome, Italy.
Yee Sin LeoNational Centre for Infectious Diseases, Singapore.
Chi-Chiu LeungHong Kong Tuberculosis, Chest and Heart Diseases Association, Wanchai, Hong Kong, China.
Anne-Grete MärtsonDept of Clinical Pharmacy and Pharmacology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.ORCID 0000-0001-6478-1959
Mario Giovanni MelazziniScientific Direction, Istituti Clinici Scientifici Maugeri IRCCS, Pavia, Italy.
Saeid Najafi FardTranslational Research Unit, Epidemiology and Preclinical Research Dept, "L. Spallanzani" National Institute for Infectious Diseases (INMI), IRCCS, Rome, Italy.
Pasi PenttinenPublic Health Emergency Team, European Centre for Disease Prevention and Control, Stockholm, Sweden.ORCID 0000-0001-6929-1086
Linda PetroneTranslational Research Unit, Epidemiology and Preclinical Research Dept, "L. Spallanzani" National Institute for Infectious Diseases (INMI), IRCCS, Rome, Italy.
Elisa PetruccioliTranslational Research Unit, Epidemiology and Preclinical Research Dept, "L. Spallanzani" National Institute for Infectious Diseases (INMI), IRCCS, Rome, Italy.
Emanuele PontaliDept of Infectious Diseases, Galliera Hospital, Genova, Italy.
Laura SaderiClinical Epidemiology and Medical Statistics Unit, Dept of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari, Italy.ORCID 0000-0002-5131-9367
Miguel SantinDept of Infectious Diseases, Bellvitge University Hospital-Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain.ORCID 0000-0002-8474-3543
Antonio SpanevelloDivision of Pulmonary Rehabilitation, Istituti Clinici Scientifici Maugeri, IRCCS, Tradate, Italy.
Reinout van CrevelRadboudumc Center for Infectious Diseases, Radboud Institute for Health Sciences, Radboudumc, Nijmegen, The Netherlands.
Marieke J van der WerfPublic Health Emergency Team, European Centre for Disease Prevention and Control, Stockholm, Sweden.ORCID 0000-0001-8021-1358
Dina ViscaDivision of Pulmonary Rehabilitation, Istituti Clinici Scientifici Maugeri, IRCCS, Tradate, Italy.ORCID 0000-0003-2298-1623
Miguel ViveirosGlobal Health and Tropical Medicine, Institute of Hygiene and Tropical Medicine, NOVA University of Lisbon, Lisbon, Portugal.
Jean-Pierre ZellwegerTB Competence Centre, Swiss Lung Association, Berne, Switzerland.
Alimuddin ZumlaDept of Infection, Division of Infection and Immunity, University College London and NIHR Biomedical Research Centre, UCL Hospitals NHS Foundation Trust, London, UK.
Delia GolettiTranslational Research Unit, Epidemiology and Preclinical Research Dept, "L. Spallanzani" National Institute for Infectious Diseases (INMI), IRCCS, Rome, Italy delia.goletti@inmi.it giovannibattista.migliori@icsmaugeri.it.
Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani · ITEuropean Centre for Disease Prevention and Control · SEIstituti Clinici Scientifici Maugeri · ITNational University of Singapore · SGThe University of Sydney · AUUniversity of Insubria · ITUniversity of Sassari · ITBellvitge University Hospital · ESEnte Ospedaliero Ospedali Galliera · ITHong Kong Tuberculosis, Chest and Heart Diseases Association · CNInserm · FRNational Centre for Infectious Diseases · SGNational Health Service · GBPennsylvania State University · USQueen Mary University of London · GBRadboud University Nijmegen · NLSt George's, University of London · GBTan Tock Seng Hospital · SGUCL Biomedical Research Centre · GBUniversità Cattolica del Sacro Cuore · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Major epidemics, including some that qualify as pandemics, such as severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), HIV, influenza A (H1N1)pdm/09 and most recently COVID-19, affect the lung. Tuberculosis (TB) remains the top infectious disease killer, but apart from syndemic TB/HIV little is known regarding the interaction of viral epidemics and pandemics with TB. The aim of this consensus-based document is to describe the effects of viral infections resulting in epidemics and pandemics that affect the lung (MERS, SARS, HIV, influenza A (H1N1)pdm/09 and COVID-19) and their interactions with TB. A search of the scientific literature was performed. A writing committee of international experts including the European Centre for Disease Prevention and Control Public Health Emergency (ECDC PHE) team, the World Association for Infectious Diseases and Immunological Disorders (WAidid), the Global Tuberculosis Network (GTN), and members of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Study Group for Mycobacterial Infections (ESGMYC) was established. Consensus was achieved after multiple rounds of revisions between the writing committee and a larger expert group. A Delphi process involving the core group of authors (excluding the ECDC PHE team) identified the areas requiring review/consensus, followed by a second round to refine the definitive consensus elements. The epidemiology and immunology of these viral infections and their interactions with TB are discussed with implications for diagnosis, treatment and prevention of airborne infections (infection control, viral containment and workplace safety). This consensus document represents a rapid and comprehensive summary on what is known on the topic.

Indexed as

BCG VaccineBetacoronavirusCoronavirus InfectionsCOVID-19EpidemicsHIV InfectionsHumansInfluenza A Virus, H1N1 SubtypeInfluenza, HumanLungMiddle East Respiratory Syndrome CoronavirusPandemicsPneumonia, ViralPublic HealthRespiratory Tract InfectionsSARS-CoV-2BCG Vaccine

Identifiers

PMID32586885
PMCPMC7527651
OpenAlexW3037036050

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.