Evidence map›Paper›PMID 32586597›Full record

ArticleEuropean journal of obstetrics, gynecology, and reproductive biology2020

Group B streptococcal disease in the mother and newborn-A review.

Philip J Steer, Alison Bedford Russell, Sonali Kochhar, Philippa Cox, Jane Plumb, Gopal Gopal Rao

Abstract read
In one paragraph

Article in European journal of obstetrics, gynecology, and reproductive biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Maternal and Newborn Group BOpen forum infectious diseases · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
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  9. Human vaccines & immunotherapeutics · 2024
    Article
  10. Article
  11. Review
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  13. Article
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  15. Article
  16. Effect of intrapartum antibiotic prophylaxis of group BZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2022
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Philip J SteerImperial College London, Academic Department of Obstetrics and Gynaecology, Chelsea and Westminster Hospital, London SW10 9NH, United Kingdom. Electronic address: p.steer@imperial.ac.uk.
Alison Bedford RussellClinical Services, Division of Neonatology, Sidra Medicine, Qatar.
Sonali KochharGlobal Healthcare Consulting, India; Department of Global Health, University of Washington, Seattle, United States.
Philippa CoxHomerton University Hospital NHS Foundation Trust, London, United Kingdom.
Jane PlumbGroup B Strep Support, Haywards Heath, RH16 1UA, United Kingdom.
Gopal Gopal RaoLondon North West University Healthcare NHS Trust, Harrow, United Kingdom.

Funding

Medical Research Council MC_PC_17221Medical Research Council MR/R005990/1Medical Research Council MR/R005990/2
6 · The paper itself

Abstract

Group B Streptococcus, a common commensal in the gut of humans and in the lower genital tract in women, remains an important cause of neonatal mortality and morbidity. The incidence of early onset disease has fallen markedly in countries that test women for carriage at 35-37 weeks of pregnancy and then offer intrapartum prophylaxis with penicillin during labour. Countries that do not test, but instead employ a risk factor approach, have not seen a similar fall. There are concerns about the effect on the neonatal microbiome of widespread use of antibiotic prophylaxis during labour, but so far the effects seem minor and temporary. Vaccination against GBS would be acceptable to most women and GBS vaccines are in the early stages of development. Tweetable abstract: Group B Strep is a key cause of infection, death and disability in young babies. Antibiotics given in labour remain the mainstay of prevention, until a vaccine is available.

Indexed as

Pregnancy Complications, InfectiousStreptococcal InfectionsAnti-Bacterial AgentsAntibiotic ProphylaxisFemaleHumansInfant, NewbornInfectious Disease Transmission, VerticalMothersPregnancyStreptococcus agalactiaeAnti-Bacterial AgentsAntibiotic prophylaxisGBSGroup B streptococcusMicrobiomeVaccine

Identifiers

PMID32586597
PMCPMC7295463

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.