Evidence map›Paper›PMID 32586523›Full record

ArticleThe Journal of pediatrics2020

Early Puberty and Telomere Length in Preadolescent Girls and Mothers.

Kalsea J Koss, Lisa M Schneper, Jeanne Brooks-Gunn, Sara McLanahan, Colter Mitchell, Daniel A Notterman

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in The Journal of pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. The epigenetic impacts of pubertal acceleration following early caregiver disruptions.Proceedings of the National Academy of Sciences of the United States of America · 2025
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  11. Phthalates and Phenols, Leukocyte Telomere Length, and Breast Cancer Risk and Mortality in the Long Island Breast Cancer Study Project.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2022
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Kalsea J KossDepartment of Human Development and Family Science, University of Georgia, Athens, GA. Electronic address: kalsea.koss@uga.edu.
Lisa M SchneperDepartment of Molecular Biology, Princeton University, Princeton, NJ.
Jeanne Brooks-GunnTeachers College, Columbia University, New York, NY.
Sara McLanahanBendheim-Thoman Center for Research on Child Wellbeing, Princeton University, Princeton, NJ.
Colter MitchellInstitute for Social Research, University of Michigan, Ann Arbor, MI.
Daniel A NottermanDepartment of Molecular Biology, Princeton University, Princeton, NJ.
Princeton University · USColumbia University · USUniversity of Georgia · USUniversity of Michigan–Ann Arbor · US

Funding

Fragile Families and the Transition to AdulthoodR01HD036916 · NICHD · PRINCETON UNIVERSITY · PI Kathryn Edin, Jane Waldfogel · 1999 to 2026
$46.3M
Reciprocal Genetic-Environmental Interactions During Childhood and AdolescenceR01HD076592 · NICHD · PRINCETON UNIVERSITY · PI NOTTERMAN, DANIEL A. · 2013 to 2023
$6.8M
Epigenetic Mediation of Adverse Social Context on Stress Response, Socioemotional Development, and Health in a Population-based Study of Minority and Low SES Children and AdolescentsR01MD011716 · NIMHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MITCHELL, COLTER M.S. · 2017 to 2022
$4.6M
Future of Families and Child Wellbeing Study Summer Data WorkshopR25HD074544 · NICHD · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Amanda Geller, Julien O Teitler · 2013 to 2026
$1.5M
NICHD NIH HHS R01 HD036916NICHD NIH HHS R01 HD076592NICHD NIH HHS R25 HD074544NIMHD NIH HHS R01 MD011716
6 · The paper itself

Abstract

objectiveTo test the association between early puberty and telomere length in preadolescent girls and mothers from a large representative sample of US females. STUDY

designWe analyzed data from 1194 preadolescent girls and 2421 mothers from the Fragile Families and Child Wellbeing Study. Participants were from a population-based birth cohort (1998-2000) born in large US cities. Telomere length was assessed by quantitative polymerase chain reaction from saliva samples provided by preadolescent girls and mothers of preadolescent youth. Mothers completed a questionnaire about their child's pubertal development to determine concurrent Tanner stages and provided self-reports of her own age at menarche. Linear regression models were used to estimate the association between pubertal development (status and timing) and telomere length.

resultsEarly pubertal timing but not pubertal status was associated with shorter telomere length in preadolescent girls (P < .01). Early age at menarche was associated with shorter telomere length in a sample of mothers of preadolescent youth (P < .05).

conclusionsResults provide evidence for the association between early puberty and shorter telomeres evidenced by associations in both preadolescent girls and mothers. Future research should address the limitations of this study by using longitudinal measurements of pubertal development assessed through medical examinations and repeated assessments of telomere length to capture telomere attrition.

Indexed as

Child DevelopmentMothersAdolescentChildFemaleHumansMenarchePubertyRetrospective StudiesTelomereTelomere HomeostasisYoung Adult

Identifiers

PMID32586523
PMCPMC7405936
OpenAlexW3035940850

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.