Evidence map›Paper›PMID 32586335›Full record

ArticleBiomedical engineering online2020

Gastric artery embolization: studying the effects of catheter type and injection method on microsphere distributions within a benchtop arterial model.

Shaphan R Jernigan, Jason A Osborne, Gregory D Buckner

Abstract read
In one paragraph

Article in Biomedical engineering online, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Developing a transcatheter injectable nanoclay- alginate gel for minimally invasive procedures.Journal of the mechanical behavior of biomedical materials · 2024
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Shaphan R JerniganDepartments of Biomedical, Mechanical and Aerospace Engineering, North Carolina State University, Raleigh, NC, 27695, USA.
Jason A OsborneDepartment of Statistics, North Carolina State University, Raleigh, NC, 27695, USA.
Gregory D BucknerDepartments of Biomedical, Mechanical and Aerospace Engineering, North Carolina State University, Raleigh, NC, 27695, USA. gbuckner@ncsu.edu.ORCID http://orcid.org/0000-0002-6601-4814

Funding

Endobar Solutions (US) 687239
6 · The paper itself

Abstract

aimsThe objective of the study is to investigate the effect of catheter type and injection method on microsphere distributions, specifically vessel targeting accuracy. MATERIALS AND

methodsThe study utilized three catheter types (a standard end-hole micro-catheter, a Surefire anti-reflux catheter, and an Endobar occlusion balloon catheter) and both manual and computer-controlled injection schemes. A closed-loop, dynamically pressurized surrogate arterial system was assembled to replicate arterial flow for bariatric embolization procedures. Four vessel branches immediately distal to the injection site were targeted for embolization. Embolic microspheres were injected into the model using these  three catheter types and both manual and computer-controlled injections.

resultsAcross all injection methods, the catheter effect on the proportion of microspheres to target vessels (vs. non-target vessels) was significant (p = 0.005). The catheter effect on the number of non-target vessels embolized was nearly significant (p = 0.059). Across all catheter types, the injection method effect was not statistically significant for either of two outcome measures (percent microspheres to target vessels: p = 0.265, number of non-target vessels embolized: p = 0.148).

conclusionCatheter type had a significant effect on targeting accuracy across all injection methods. The Endobar catheter exhibited a higher targeting accuracy in pairwise comparisons with the other two injection catheters across all injection schemes and when considering the Endobar catheter with the manifold injection method vs. each of the catheters with the manual injection method; the differences were significant in three of four analyses. The injection method effect was not statistically significant across all catheter types and when considering the Endobar catheter/Endobar manifold combination vs. Endobar catheter injections with manual and pressure-replicated methods.

Indexed as

CathetersGastric ArteryMicrospheresEmbolization, TherapeuticHumansInjectionsEmbolizationGastric arteryRefluxVessel targeting

Identifiers

PMID32586335
PMCPMC7318750

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.