Evidence map›Paper›PMID 32586315›Full record

SynthesisBMC oral health2020

Treating periodontitis-a systematic review and meta-analysis comparing ultrasonic and manual subgingival scaling at different probing pocket depths.

Xin Zhang, Zixuan Hu, Xuesong Zhu, Wenjie Li, Jun Chen

Registry-linked trialOpen access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BMC oral health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07487285 (A Non-inferiority Study of Laser Combined With Ultrasonic Debridement Therapy), which is not on this map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07487285 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

A Non-inferiority Study of Laser Combined With Ultrasonic Debridement Therapy (LCUDT) Versus Manual Combined With Ultrasonic Debridement Therapy (MCUDT) in the Treatment of Periodontitis

TypeinterventionalSponsorSecond Affiliated Hospital, Zhejiang University, School of MedicineRan2026 to 2027Enrolled174ConditionsPeriodontitis, Periodontal DebridementArmsExperimental: Laser Combined with Ultrasonic Debridement Therapy, Active Comparator: Manual Combined with Ultrasonic Debridement Therapy
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
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  3. Student Perspectives on the Efficacy of Hybrid Simulation Laboratory Teaching-Practicing Modules.European journal of dental education : official journal of the Association for Dental Education in Europe · 2026
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  8. IL-6Journal of translational medicine · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Xin ZhangDepartment of Orthodontics, Xiangya School of Stomatology, Central South University, Changsha, 410008, People's Republic of China.ORCID 0000-0001-5825-7229
Zixuan HuDepartment of Orthodontics, Xiangya School of Stomatology, Central South University, Changsha, 410008, People's Republic of China.ORCID 0000-0003-0939-4440
Xuesong ZhuDepartment of Orthodontics, Xiangya School of Stomatology, Central South University, Changsha, 410008, People's Republic of China.ORCID 0000-0001-9183-1675
Wenjie LiDepartment of Orthodontics, Xiangya School of Stomatology, Central South University, Changsha, 410008, People's Republic of China.ORCID 0000-0003-4195-6351
Jun ChenHunan Key Laboratory of Oral Health Research, Hunan 3D Printing Engineering Research Center of Oral Care, Hunan Clinical Research Center of Oral Major Diseases and Oral Health, Central South University, Changsha, 410008, People's Republic of China. chenjun1222@csu.edu.cn.ORCID 0000-0003-3265-0318
Central South University · CN

Funding

the National-level College Students' Innovative Entrepreneurial Training Plan Program of China S201910533045the Natural Science Foundation of Hunan Province for Young Scientists, China 2019JJ50784the Young Teacher's Institutional grant from Xiangya School of Stomatology and Xiangya Stomatological Hospital, Central South University 2018YQ02
6 · The paper itself

Abstract

backgroundMechanical plaque removal has been commonly accepted to be the basis for periodontal treatment. This study aims to compare the effectiveness of ultrasonic and manual subgingival scaling at different initial probing pocket depths (PPD) in periodontal treatment.

methodsEnglish-language databases (PubMed, Cochrane Central Register of Controlled Trials, EMBASE, Medline, and ClinicalTrials.gov, by January, 2019) were searched. Weighted mean differences in primary outcomes, PPD and clinical attachment loss (CAL) reduction, were estimated by random effects model. Secondary outcomes, bleeding on probing (BOP), gingival recession (GR), and post-scaling residual dental calculus, were analyzed by comparing the results of each study. The quality of RCTs was appraised with the Cochrane Collaboration risk of bias tool. The GRADE approach was used to assess quality of evidence.

resultsTen randomized controlled trials were included out of 1434 identified. Initial PPD and follow-up periods formed subgroups. For 3-months follow-up: (1) too few shallow initial pocket studies available to draw a conclusion; (2) the heterogeneity of medium depth studies was so high that could not be merged to draw a conclusion; (3) deep pocket studies showed no statistical differences in PPD and CAL reduction between ultrasonic and manual groups. For 6-months follow-up: (1) too few shallow initial PPD studies to draw a conclusion; (2) at medium pocket depth, PPD reduction showed manual subgingival scaling better than ultrasound. No statistical differences were observed in CAL reduction between the two approaches; (3) for deep initial PPD studies, both PPD and CAL reduction showed manual subgingival scaling better. GR results indicated no statistical differences at medium and deep initial pocket studies between the two methods. BOP results showed more reduction at deep pocket depths with manual subgingival scaling. No conclusion could be drawn about residual dental calculus.

conclusionWhen initial PPD was 4-6 mm, PPD reduction proved manual subgingival scaling was superior, but CAL results showed no statistical differences between the two means. When initial PPD was ≥6 mm, PPD and CAL reductions suggested that manual subgingival scaling was superior.

Indexed as

Dental ScalingUltrasonicsHumansPeriodontal PocketPeriodontitisPilot ProjectsProspective StudiesRandomized Controlled Trials as TopicMeta-analysisPeriodontal debridementPeriodontal pocketSubgingival scalingUltrasonic therapy

Identifiers

PMID32586315
PMCPMC7318456
OpenAlexW3037665080

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.