Evidence map›Paper›PMID 32586085›Full record

ArticleTurkish journal of haematology : official journal of Turkish Society of Haematology2020

Sema Sırma Ekmekci, Zeliha Emrence, Neslihan Abacı, Melda Sarıman, Burcu Salman, Cumhur Gökhan Ekmekci, Çağrı Güleç

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Turkish journal of haematology : official journal of Turkish Society of Haematology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.1field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Sema Sırma Ekmekciİstanbul University, Aziz Sancar Institute of Experimental Medicine, Department of Genetics, İstanbul, TurkeyORCID 0000-0002-1201-7542
Zeliha Emrenceİstanbul University, Aziz Sancar Institute of Experimental Medicine, Department of Genetics, İstanbul, TurkeyORCID 0000-0003-4809-6366
Neslihan Abacıİstanbul University, Aziz Sancar Institute of Experimental Medicine, Department of Genetics, İstanbul, TurkeyORCID 0000-0002-9962-4010
Melda Sarımanİstanbul University, Aziz Sancar Institute of Experimental Medicine, Department of Genetics, İstanbul, TurkeyORCID 0000-0003-0898-529X
Burcu Salmanİstanbul University, Aziz Sancar Institute of Experimental Medicine, Department of Genetics, İstanbul, TurkeyORCID 0000-0002-9144-3899
Cumhur Gökhan Ekmekciİstanbul University, Aziz Sancar Institute of Experimental Medicine, Department of Genetics, İstanbul, TurkeyORCID 0000-0002-0967-172X
Çağrı Güleçİstanbul University, Aziz Sancar Institute of Experimental Medicine, Department of Genetics, İstanbul, Turkey
Istanbul University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive disease resulting from the accumulation of genetic changes that affect the development of T-cells. The precise role of lymphoid enhancer-binding factor 1 ( Materials and Methods: We used small interfering RNA (siRNA) technology to knock down Results: We identified Conclusion: Our results revealed that

Indexed as

Gene Expression Regulation, LeukemicBiomarkers, TumorCarbonyl Reductase (NADPH)Computational BiologyHumansJurkat CellsLymphoid Enhancer-Binding Factor 1Precursor T-Cell Lymphoblastic Leukemia-LymphomaRNA InterferenceRNA, MessengerRNA, Small InterferingBiomarkers, TumorCarbonyl Reductase (NADPH)DHRS2 protein, humanLEF1 protein, humanLymphoid Enhancer-Binding Factor 1RNA, MessengerRNA, Small InterferingDHRS2LEF1p53siRNAT-cell acute lymphoblastic leukemia

Identifiers

PMID32586085
PMCPMC7702649
OpenAlexW3037657567

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.