Evidence map›Paper›PMID 32586001›Full record

ArticleNanomaterials (Basel, Switzerland)2020

Identification of a Profile of Neutrophil-Derived Granule Proteins in the Surface of Gold Nanoparticles after Their Interaction with Human Breast Cancer Sera.

María Del Pilar Chantada-Vázquez, María García-Vence, Sergio Vázquez-Estévez, Susana B Bravo, Cristina Núñez

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

María Del Pilar Chantada-VázquezResearch Unit, Hospital Universitario Lucus Augusti (HULA), Servizo Galego de Saúde (SERGAS), 27002 Lugo, Spain.
María García-VenceProteomic Unit, Instituto de Investigaciones Sanitarias, Complejo Hospitalario Universitario de Santiago de Compostela (IDIS-CHUS), 15706 Santiago de Compostela, Spain.
Sergio Vázquez-EstévezOncology Division, Hospital Universitario Lucus Augusti (HULA), Servizo Galego de Saúde (SERGAS), 27002 Lugo, Spain.
Susana B BravoProteomic Unit, Instituto de Investigaciones Sanitarias, Complejo Hospitalario Universitario de Santiago de Compostela (IDIS-CHUS), 15706 Santiago de Compostela, Spain.ORCID 0000-0001-7615-3079
Cristina NúñezResearch Unit, Hospital Universitario Lucus Augusti (HULA), Servizo Galego de Saúde (SERGAS), 27002 Lugo, Spain.ORCID 0000-0003-1554-9891
Complejo Hospitalario Universitario de Santiago · ESHospital Universitario Lucus Augusti · ES

Funding

Instituto de Salud Carlos III CP16/00139
6 · The paper itself

Abstract

It is well known that the interaction of a nanomaterial with a biological fluid leads to the formation of a protein corona (PC) surrounding the nanomaterial. Using standard blood analyses, alterations in protein patterns are difficult to detect. PC acts as a "nano-concentrator" of serum proteins with affinity for nanoparticles' surface. Consequently, characterization of PC could allow detection of otherwise undetectable changes in protein concentration at an early stage of a disease, such as breast cancer (BC). Here, we employed gold nanoparticles (AuNPs

Indexed as

breast cancer (BC)gold nanoparticles (AuNPs)mass spectrometry (MS)neutrophilsprotein biomarkerssurface

Identifiers

PMID32586001
PMCPMC7353125
OpenAlexW3036848258

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.