ArticleMicroorganisms2020
Cryo-EM Structure and Molecular Dynamics Analysis of the Fluoroquinolone Resistant Mutant of the AcrB Transporter from
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Article in Microorganisms, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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0cells of the map it votes in
22citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
What it found
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Who cites it
22 citing papers in PubMed, 29 citations in OpenAlex.
- Insights into substrate recognition and export tunnel preferences in the efflux transporter AcrB.Protein science : a publication of the Protein Society · 2025Article
- Structural and functional diversity of Resistance-Nodulation-Division (RND) efflux pump transporters with implications for antimicrobial resistance.Microbiology and molecular biology reviews : MMBR · 2024Review
- Role of Protonation States in the Stability of Molecular Dynamics Simulations of High-Resolution Membrane Protein Structures.The journal of physical chemistry. B · 2024Article
- Isolation, Identification, Antimicrobial Resistance, Genotyping, and Whole-Genome Sequencing Analysis ofPolish journal of microbiology · 2024Article
- Molecular insights into the determinants of substrate specificity and efflux inhibition of the RND efflux pumps AcrB and AdeB.Microbiology (Reading, England) · 2024Review
- Genotypic Antimicrobial Resistance Profiles of DiarrheagenicInfection and drug resistance · 2024Article
- RND pumps across the genusMicrobial genomics · 2023Article
- Functionally distinct mutations within AcrB underpin antibiotic resistance in different lifestyles.npj antimicrobials and resistance · 2023Article
- Detergent-Free Isolation of Membrane Proteins and Strategies to Study Them in a Near-Native Membrane Environment.Biomolecules · 2022Review
- Common recognition topology of mex transporters ofFrontiers in pharmacology · 2022Article
- Structure-function analysis of MmpL7-mediated lipid transport in mycobacteria.Cell surface (Amsterdam, Netherlands) · 2021Article
- Cycloalkane-modified amphiphilic polymers provide direct extraction of membrane proteins for CryoEM analysis.Communications biology · 2021Article
- The Transporter-Mediated Cellular Uptake and Efflux of Pharmaceutical Drugs and Biotechnology Products: How and Why Phospholipid Bilayer Transport Is Negligible in Real Biomembranes.Molecules (Basel, Switzerland) · 2021Review
- Interchangeability of periplasmic adaptor proteins AcrA and AcrE in forming functional efflux pumps with AcrD in Salmonella enterica serovar Typhimurium.The Journal of antimicrobial chemotherapy · 2021Article
- Structural Insights into Transporter-Mediated Drug Resistance in Infectious Diseases.Journal of molecular biology · 2021Review
- Detergent-free systems for structural studies of membrane proteins.Biochemical Society transactions · 2021Review
- Ever-Adapting RND Efflux Pumps in Gram-Negative Multidrug-Resistant Pathogens: A Race against Time.Antibiotics (Basel, Switzerland) · 2021Review
- Structures and Dynamics of Native-State Transmembrane Protein Targets and Bound Lipids.Membranes · 2021Review
- Structure, Assembly, and Function of Tripartite Efflux and Type 1 Secretion Systems in Gram-Negative Bacteria.Chemical reviews · 2021Review
- Changes in Membrane Protein Structural Biology.Biology · 2020Review
Corrections and comments
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Authors and funding
12 authors at 5 institutions in 2 countries.
Rachel M JohnsonSchool of Biomedical Sciences, Faculty of Biological Sciences & Astbury Centre for Structural and Molecular Biology, University of Leeds, Leeds LS2 9JT, UK.
Chiara FaisDepartment of Physics, University of Cagliari, s.p. 8, Cittadella Universitaria, 09042 Monserrato, Italy.
Mayuriben ParmarBiomedicine Research Group, Faculty of Health and Social Sciences, Leeds Beckett University, Leeds LS1 3HE, UK.
Harish CheruvaraDiamond Light Source, Membrane Protein Laboratory (MPL), Diamond House, Harwell Science and Innovation Campus, Fermi Ave, Didcot OX11 0DE, UK.ORCID 0000-0001-7688-0401
Robert L MarshallSchool of Biosciences, University of Birmingham, Birmingham B15 2TT, UK.
Sophie J HeskethSchool of Biomedical Sciences, Faculty of Biological Sciences & Astbury Centre for Structural and Molecular Biology, University of Leeds, Leeds LS2 9JT, UK.
Matthew C FeaseySchool of Biomedical Sciences, Faculty of Biological Sciences & Astbury Centre for Structural and Molecular Biology, University of Leeds, Leeds LS2 9JT, UK.
Paolo RuggeroneDepartment of Physics, University of Cagliari, s.p. 8, Cittadella Universitaria, 09042 Monserrato, Italy.
Attilio V VargiuDepartment of Physics, University of Cagliari, s.p. 8, Cittadella Universitaria, 09042 Monserrato, Italy.ORCID 0000-0003-4013-8867
Vincent L G PostisBiomedicine Research Group, Faculty of Health and Social Sciences, Leeds Beckett University, Leeds LS1 3HE, UK.
Stephen P MuenchSchool of Biomedical Sciences, Faculty of Biological Sciences & Astbury Centre for Structural and Molecular Biology, University of Leeds, Leeds LS2 9JT, UK.ORCID 0000-0001-6869-4414
Vassiliy N BavroSchool of Life Sciences, University of Essex, Wivenhoe Park, Colchester CO4 3SQ, UK.ORCID 0000-0003-2330-8924
University of Leeds · GBUniversity of Cagliari · ITLeeds Beckett University · GBUniversity of Essex · GBUniversity of Birmingham · GB
Funding
Optimization of efflux avoidance and inhibition for antibiotic developmentR01AI136799 · NIAID · UNIVERSITY OF OKLAHOMA · PI GNANAKARAN, SANDRASEGARAM, RUGGERONE, PAOLO · 2018 to 2022
$5.7MBiotechnology and Biological Sciences Research Council BB/N002776/1National Institutes of Allergy and Infectious Diseases AI136799Wellcome Trust 108372/A/15/ZWellcome Trust 108466/Z/15/ZWellcome Trust 109158/B/15/Z
Abstract
PubMed holds no abstract for this paper.
Indexed as
AcrBcryo-EMmembrane proteinsmolecular dynamicsmultidrug efflux pumpmultidrug resistanceSalmonella
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.