Evidence map›Paper›PMID 32585916›Full record

ArticleMolecules (Basel, Switzerland)2020

Arterial Hypertension and Plasma Glucose Modulate the Vasoactive Effects of Nitroso-Sulfide Coupled Signaling in Human Intrarenal Arteries.

Sona Cacanyiova, Katarina Krskova, Stefan Zorad, Karel Frimmel, Magdalena Drobna, Zuzana Valaskova, Anton Misak, Samuel Golas, Jan Breza, Jan Breza and 1 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
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  6. Review
  7. Cardiovascular "Patterns" of HBiomolecules · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Sona CacanyiovaInstitute of Normal and Pathological Physiology, Center of Experimental Medicine, Slovak Academy of Sciences, 841 04 Bratislava, Slovakia.
Katarina KrskovaInstitute of Experimental Endocrinology, Biomedical Research Center, Slovak Academy of Sciences, 845 05 Bratislava, Slovakia.
Stefan ZoradInstitute of Experimental Endocrinology, Biomedical Research Center, Slovak Academy of Sciences, 845 05 Bratislava, Slovakia.
Karel FrimmelInstitute for Heart Research, Center of Experimental Medicine, Slovak Academy of Sciences, 841 04 Bratislava, Slovakia.
Magdalena DrobnaInstitute of Normal and Pathological Physiology, Center of Experimental Medicine, Slovak Academy of Sciences, 841 04 Bratislava, Slovakia.
Zuzana ValaskovaInstitute of Normal and Pathological Physiology, Center of Experimental Medicine, Slovak Academy of Sciences, 841 04 Bratislava, Slovakia.
Anton MisakInstitute of Clinical and Translational Research, Biomedical Research Center, Slovak Academy of Sciences, 845 05 Bratislava, Slovakia.
Samuel GolasInstitute of Normal and Pathological Physiology, Center of Experimental Medicine, Slovak Academy of Sciences, 841 04 Bratislava, Slovakia.
Jan BrezaDepartment of Urology, Derer's University Hospital, 833 05 Bratislava, Slovakia.
Jan BrezaDepartment of Urology, Derer's University Hospital, 833 05 Bratislava, Slovakia.
Andrea BerenyiovaInstitute of Normal and Pathological Physiology, Center of Experimental Medicine, Slovak Academy of Sciences, 841 04 Bratislava, Slovakia.
Slovak Academy of Sciences · SKInstitute of Normal and Pathological Physiology of the Slovak Academy of Sciences · SKUniversity Hospital Bratislava · SKBiomedical Research Center of the Slovak Academy of Sciences · SKInstitute of Experimental Endocrinology of the Slovak Academy of Sciences · SK

Funding

Scientific Grant Agency of The Ministry of Education, Science, Research and Sport of the Slovak Republic VEGA 2/0103/18, VEGA 2/0079/19, VEGA 2/0162/19Slovak Research and Development Agency APVV-15-0565
6 · The paper itself

Abstract

We have investigated the vasoactive effects of the coupled nitro-sulfide signaling pathway in lobar arteries (LAs) isolated from the nephrectomized kidneys of cancer patients: normotensive patients (NT) and patients with arterial hypertension (AH). LAs of patients with AH revealed endothelial dysfunction, which was associated with an increased response to the exogenous NO donor, nitrosoglutathione (GSNO). The interaction of GSNO with the H

Indexed as

Signal TransductionAnimalsBlood GlucoseCystathionine beta-SynthaseCystathionine gamma-LyaseFemaleGene Expression Regulation, EnzymologicGlutathioneHumansHypertensionMaleMiddle AgedNitric OxideProtein TransportRatsRenal ArteryBlood GlucoseCystathionine beta-SynthaseCystathionine gamma-LyaseGlutathioneNitric OxideSerotoninSulfidesarterial hypertensionCBSCTH gene expressionhuman lobar arteryhydrogen sulfideimmunofluorescencenitroso-sulfide signalingnormotensiveS-nitrosoglutathione

Identifiers

PMID32585916
PMCPMC7356001
OpenAlexW3036709056

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.