Evidence map›Paper›PMID 32585891›Full record

ArticleMarine drugs2020

In Vitro and In Vivo Assessment of the Efficacy of Bromoageliferin, an Alkaloid Isolated from the Sponge

Dawrin Pech-Puch, Mar Pérez-Povedano, Marta Martinez-Guitian, Cristina Lasarte-Monterrubio, Juan Carlos Vázquez-Ucha, Germán Bou, Jaime Rodríguez, Alejandro Beceiro, Carlos Jimenez

Abstract read
In one paragraph

Article in Marine drugs, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  7. β-Lactams from the Ocean.Marine drugs · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Dawrin Pech-PuchCentro de Investigacións Científicas Avanzadas (CICA) e Departamento de Química, Facultade de Ciencias, AE CICA-INIBIC, Universidade da Coruña, 15071 A Coruña, Spain.ORCID 0000-0002-1680-4340
Mar Pérez-PovedanoCentro de Investigacións Científicas Avanzadas (CICA) e Departamento de Química, Facultade de Ciencias, AE CICA-INIBIC, Universidade da Coruña, 15071 A Coruña, Spain.
Marta Martinez-GuitianServicio de Microbioloxía, Instituto de Investigación Biomédica, AE CICA-INIBIC Complexo Hospitalario Universitario A Coruña, 15006 A Coruña, Spain.
Cristina Lasarte-MonterrubioServicio de Microbioloxía, Instituto de Investigación Biomédica, AE CICA-INIBIC Complexo Hospitalario Universitario A Coruña, 15006 A Coruña, Spain.ORCID 0000-0003-3351-2064
Juan Carlos Vázquez-UchaServicio de Microbioloxía, Instituto de Investigación Biomédica, AE CICA-INIBIC Complexo Hospitalario Universitario A Coruña, 15006 A Coruña, Spain.ORCID 0000-0003-4949-0779
Germán BouServicio de Microbioloxía, Instituto de Investigación Biomédica, AE CICA-INIBIC Complexo Hospitalario Universitario A Coruña, 15006 A Coruña, Spain.
Jaime RodríguezCentro de Investigacións Científicas Avanzadas (CICA) e Departamento de Química, Facultade de Ciencias, AE CICA-INIBIC, Universidade da Coruña, 15071 A Coruña, Spain.ORCID 0000-0001-5348-6970
Alejandro BeceiroServicio de Microbioloxía, Instituto de Investigación Biomédica, AE CICA-INIBIC Complexo Hospitalario Universitario A Coruña, 15006 A Coruña, Spain.
Carlos JimenezCentro de Investigacións Científicas Avanzadas (CICA) e Departamento de Química, Facultade de Ciencias, AE CICA-INIBIC, Universidade da Coruña, 15071 A Coruña, Spain.ORCID 0000-0003-2628-303X

Funding

BLUEBIOLAB (0474_BLUEBIOLAB_1_E), Programme INTERREG V A of Spain-Portugal (POCTEP). 0474_BLUEBIOLAB_1_EpFIS Program FI18/00315State Agency for Research (AEI) of Spain RTI2018-093634-B-C22
6 · The paper itself

Abstract

The pyrrole-imidazoles, a group of alkaloids commonly found in marine sponges belonging to the genus

Indexed as

Acinetobacter baumanniiAgelasAlkaloidsAnimalsAnti-Bacterial AgentsBiofilmsKlebsiella pneumoniaeMexicoMolecular StructurePoriferaPseudomonas aeruginosaAlkaloidsAnti-Bacterial AgentsAgelas dilatataantibacterialbiofilm inhibitionGalleria mellonellaPseudomonas aeruginosapyrrole-imidazole alkaloidsstructure-activity relationshipsYucatan Peninsula

Identifiers

PMID32585891
PMCPMC7345159

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.