ArticleGerontology2020
Immunological Implications of Physical Inactivity among Older Adults during the COVID-19 Pandemic.
Article in Gerontology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
58 citing papers in PubMed, 147 citations in OpenAlex.
- Short Multicomponent Group Exercise Intervention Promotes Long-Term Physical Activity Habits among Community-Dwelling Older Adults during COVID-19 Restrictions: A Cohort Study.International journal of environmental research and public health · 2022Trial
- No independent associations between physical activity and clinical outcomes among hospitalized patients with moderate to severe COVID-19.Journal of sport and health science · 2021Trial
- Physical Activity Patterns, Psychosocial Well-Being and Coping Strategies Among Older Persons with Cognitive Frailty of the "WE-RISE" Trial Throughout the COVID-19 Movement Control Order.Clinical interventions in aging · 2021Trial
- Accelerometry-measured prolonged and interrupted sedentary behavior and cancer incidence and mortality: A cohort study of 91,292 UK Biobank participants.PLoS medicine · 2026Article
- [Trends of disease burden on spinal cord injury in China from 1990 to 2023].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2026Article
- Immune-Enhancement Effects of 6-Methoxykaempferol on Cyclophosphamide-Induced Immunosuppression via Improving Antioxidant Enzyme Expression, NF-κB and MAPK Signaling, and Modulating Gut Microbiome.Antioxidants (Basel, Switzerland) · 2026Article
- Implementation of Telehealth Among Older People: A Challenge and Opportunity for Latin America and the Caribbean-A Literature Review.Healthcare (Basel, Switzerland) · 2025Review
- The Psychophysiological Relaxation Effects of Essential Oil Combined with Still-Life Painting Activities on Older Adults in Taiwan During the COVID-19 Pandemic.Applied psychophysiology and biofeedback · 2025Article
- Community-Dwelling Filipino Older Adults' Experiences with Virtual Coach for Health-Enhancing Physical Activity (HEPA): A Phenomenology.Nursing reports (Pavia, Italy) · 2025Article
- Predictors of cigarette smoking and physical inactivity among teachers during the SARS-CoV-2 pandemic in Germany: a cross-sectional analysis of a nationwide online survey.Frontiers in public health · 2025Article
- Hospital-Onset Sepsis Warrants Expanded Investigation and Consideration as a Unique Clinical Entity.Chest · 2024Review
- Device-assessed physical activity and sleep quality of post-COVID patients undergoing a rehabilitation program.BMC sports science, medicine & rehabilitation · 2024Article
- Assessing the Impact of COVID-19 on Amateur Runners' Performance: An Analysis through Monitoring Devices.Sensors (Basel, Switzerland) · 2024Article
- A virtually supervised exercise program improved fitness and mental wellness in healthy and comorbidity older adult individuals during the COVID-19 pandemic.Frontiers in public health · 2024Article
- Prevalence and factors associated with the death of older people hospitalized due to Covid-19 in the state of Paraná.Revista da Escola de Enfermagem da U S P · 2024Article
- Physical activity status prevents symptoms of long covid: Sulcovid-19 survey.BMC sports science, medicine & rehabilitation · 2023Article
- A higher frequency of physical activity is associated with reduced rates of SARS-CoV-2 infection.The European journal of general practice · 2023Article
- A Comparison of Cognitive Performance, Depressive Symptoms, and Incidence of Falls in Brazilian Older Women with and without a Confirmed History of COVID-19.International journal of environmental research and public health · 2023Article
- Coping with the COVID-19 pandemic by strengthening immunity as a nonpharmaceutical intervention: A major public health challenge.Health science reports · 2023Article
- Secreted Protein Acidic and Rich in Cysteine (SPARC) to Manage Coronavirus Disease-2019 (COVID-19) Pandemic and the Post-COVID-19 Health Crisis.Medicines (Basel, Switzerland) · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Social distancing has been adopted worldwide to control severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission. Social isolation is likely to lead to a decline in physical activity, which could result in immune system dysfunction, thereby increasing infection susceptibility and exacerbating the pathophysiology of conditions that are common among older adults, including cardiovascular disease, cancer, and inflammatory disorders. Older adults and people living with these comorbidities are at a greater risk for complications during coronavirus disease 2019 (COVID-19). In this review, we discuss the negative impact of physical inactivity on immune function and showcase evidence that regular physical activity may be an effective strategy to counter some of the deleterious effects of social isolation. Furthermore, we briefly highlight key research questions in exercise immunology, with a focus on older adults in the context of COVID-19. Although it is worth emphasizing that there is no direct evidence that physical activity can prevent or treat -COVID-19, promoting an active lifestyle is a key intervention to counteract the effects of social isolation, especially in older adults and other at-risk individuals, such as those living with chronic diseases associated with ageing and lifestyle.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.