Evidence map›Paper›PMID 32585625›Full record

ReviewMolecular therapy. Nucleic acids2020

Regulatory Roles of Circular RNAs in Coronary Artery Disease.

Shuchen Zhang, Wenjing Wang, Xiaoguang Wu, Xiang Zhou

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Molecular therapy. Nucleic acids, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Pooled it
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  11. Circular RNAs Variously Participate in Coronary Atherogenesis.Current issues in molecular biology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Shuchen ZhangDepartment of Cardiology, The Second Affiliated Hospital of Soochow University, Suzhou 215004, P.R. China.
Wenjing WangDepartment of Cardiology, The Second Affiliated Hospital of Soochow University, Suzhou 215004, P.R. China.
Xiaoguang WuDepartment of Cardiology, The Second Affiliated Hospital of Soochow University, Suzhou 215004, P.R. China.
Xiang ZhouDepartment of Cardiology, The Second Affiliated Hospital of Soochow University, Suzhou 215004, P.R. China. Electronic address: zhou-xiang@suda.edu.cn.
Second Affiliated Hospital of Soochow University · CNSoochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronary artery disease (CAD) is a cardiac disorder caused by abnormal structure or function of the coronary artery, which leads to myocardial ischemia and hypoxia. CAD is a major cause of morbidity and mortality worldwide. Although there are currently effective drug therapies, there is a pressing need to find novel molecular therapeutic targets for CAD. The development of molecular biology technology has allowed the recognition of circular RNAs (circRNAs) as a novel class of noncoding RNAs that regulate gene function. The pathological roles of circRNAs in CAD have not, however, been comprehensively summarized. In this article, we review published research linking circRNAs to CAD and summarize the regulatory roles of circRNAs in the pathogenesis of coronary atherosclerosis, myocardial infarction, ischemia/reperfusion injury, and ischemic heart failure.

Indexed as

circular RNAscoronary artery diseasepathogenesis

Identifiers

PMID32585625
PMCPMC7321795
OpenAlexW3028389147

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.