Evidence map›Paper›PMID 32585236›Full record

ArticleRadiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology2020

Patterns of practice for adaptive and real-time radiation therapy (POP-ART RT) part I: Intra-fraction breathing motion management.

Gail Anastasi, Jenny Bertholet, Per Poulsen, Toon Roggen, Cristina Garibaldi, Nina Tilly, Jeremy T Booth, Uwe Oelfke, Ben Heijmen, Marianne C Aznar

Open access · hybridAbstract read
In one paragraph

Article in Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
8.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 57 citations in OpenAlex.

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  10. Artificial intelligence for treatment delivery: image-guided radiotherapy.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2025
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  20. The role of 4D particle therapy in daily patient care and research.Physics and imaging in radiation oncology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 9 institutions in 7 countries.

Gail AnastasiSt. Luke's Cancer Centre, Royal Surrey Foundation Trust, Radiotherapy Physics, Guildford, United Kingdom. Electronic address: gail.distefano@nhs.net.
Jenny BertholetThe Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, Joint Department of Physics, London, United Kingdom; Division of Medical Radiation Physics, Department of Radiation Oncology, Inselspital, Bern University Hospital, Switzerland.
Per PoulsenAarhus University Hospital, Department of Oncology and Danish Center for Particle Therapy, Aarhus, Denmark.
Toon RoggenVarian Medical Systems Imaging Laboratory GmbH, Applied Research, Dättwil AG, Switzerland.
Cristina GaribaldiEuropean Institute of Oncology IRCCS, IEO-Unit of Radiation Research, Milan, Italy.
Nina TillyElekta Instruments AB, Stockholm, Sweden; Medical Radiation Physics, Department of Immunology, Genetics and Pathology, Uppsala University, Sweden.
Jeremy T BoothRoyal North Shore Hospital, Northern Sydney Cancer Centre, Australia.
Uwe OelfkeThe Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, Joint Department of Physics, London, United Kingdom.
Ben HeijmenErasmus MC Cancer Institute, Department of Radiation Oncology, Rotterdam, Netherlands.
Marianne C AznarDivision of Cancer Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, The Christie NHS Foundation Trust, Manchester, United Kingdom; Nuffield Department of Population Health, University of Oxford, United Kingdom.
Royal Marsden NHS Foundation Trust · GBAarhus University Hospital · DKErasmus MC Cancer Institute · NLIstituti di Ricovero e Cura a Carattere Scientifico · ITRoyal North Shore Hospital · AURoyal Surrey NHS Foundation Trust · GBUniversity of Manchester · GBUppsala University · SEVarian Medical Systems (Switzerland) · CH

Funding

Cancer Research UK 21133Cancer Research UK 28284Cancer Research UK C33589/A19727Cancer Research UK C33589/A19908Cancer Research UK C8225/A21133Department of Health DRF-2018-11-ST2-067Medical Research Council MC_U137686858
6 · The paper itself

Abstract

purposeThe POP-ART RT study aims to determine to what extent and how intra-fractional real-time respiratory motion management (RRMM) and plan adaptation for inter-fractional anatomical changes (ART), are used in clinical practice and to understand barriers to implementation. Here we report on part I: RRMM. MATERIAL AND

methodsA questionnaire was distributed worldwide to assess current clinical practice, wishes for expansion or new implementation and barriers to implementation. RRMM was defined as inspiration/expiration gating in free-breathing or breath-hold, or tracking where the target and the beam are continuously realigned.

resultsThe questionnaire was completed by 200 centres from 41 countries. RRMM was used by 68% of respondents ('users') for a median (range) of 2 (1-6) tumour sites. Eighty-one percent of users applied inspiration breath-hold in at least one tumour site (breast: 96%). External marker was used to guide RRMM by 61% of users. KV/MV imaging was frequently used for liver and pancreas (with fiducials) and for lung (with or without fiducials). Tracking was mainly performed on robotic linacs with hybrid internal-external monitoring. For breast and lung, approximately 75% of respondents used or wished to implement RRMM, which was lower for liver (44%) and pancreas (27%). Seventy-one percent of respondents wished to implement RRMM for a new tumour site. Main barriers were human/financial resources and capacity on the machine.

conclusionSixty-eight percent of respondents used RRMM and 71% wished to implement RRMM for a new tumour site. The main barriers to implementation were human/financial resources and capacity on treatment machines.

Indexed as

Lung NeoplasmsRespirationHumansLungMotionRadiotherapy Planning, Computer-AssistedBreath holdGatingIntra-fractional motionReal-time respiratory motion managementTumour tracking

Identifiers

PMID32585236
PMCPMC7758783
OpenAlexW3037150150

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.